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题名: A phase-segregated model for plant cell culture: The effect of cell volume fraction
作者: Zhang, W;  Furusaki, S;  Middelberg, APJ
关键词: plant cell culture ;  phase-segregated ;  modeling ;  cell volume fraction (CVF) ;  structured model
刊名: JOURNAL OF CHEMICAL ENGINEERING OF JAPAN
发表日期: 1998-06-01
卷: 31, 期:3, 页:469-474
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Technology
类目[WOS]: Engineering, Chemical
研究领域[WOS]: Engineering
英文摘要: Plant cells are characterized by low water content, so the fraction of cell volume (volume fraction) in a vessel is large compared with other cell systems, even if the cell concentrations are the same. Therefore, concentration of plant cells should preferably be expressed by the liquid volume basis rather than by the total vessel volume basis. In this paper, a new model is proposed to analyze behavior of a plant cell culture by dividing the cell suspension into the biotic- and abiotic-phases, Using this model, we analyzed the cell-growth and the alkaloid production by Catharanthus roseus, Large errors in the simulated results were observed if the phase-segregation was not considered.
关键词[WOS]: CATHARANTHUS-ROSEUS ;  SUSPENSION CULTURES ;  STRUCTURED MODEL ;  GROWTH-KINETICS ;  SHAKE FLASK ;  TEMPERATURE ;  BIOREACTORS ;  FERMENTERS
语种: 英语
WOS记录号: WOS:000074596600023
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138108
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Univ Adelaide, Dept Chem Engn, Adelaide, SA 5005, Australia
2.Univ Tokyo, Grad Sch Engn, Dept Chem & Biotech, Tokyo 113, Japan
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dept Biochem Engn, Dalian 116012, Peoples R China

Recommended Citation:
Zhang, W,Furusaki, S,Middelberg, APJ. A phase-segregated model for plant cell culture: The effect of cell volume fraction[J]. JOURNAL OF CHEMICAL ENGINEERING OF JAPAN,1998,31(3):469-474.
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