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题名: Analysis of biomembrane permeable compounds and quality control in combined prescription of traditional Chinese medicine by immobilized liposome chromatography
作者: Sheng, LH;  Li, RY;  Li, P;  Zou, HF;  Kong, L
关键词: immobilized liposome chromatography ;  combined prescription of traditional Chinese medicine ;  combined prescription of Danggui Buxue decoction ;  biomembrane permeable component ;  quality control
刊名: CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
发表日期: 2004-12-01
卷: 32, 期:12, 页:1595-1598
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: A new method of immobilized liposome chromatography (ILC) was proposed to analyse the biomembrane permeable compounds in combined prescription of traditional Chinese medicine. Separation for the extracts of combined prescription of Danggui Buxue decoction and its compositions with different extract processes on ILC column was compared, it was found that there are respectively 8 peaks with significant retention on ILC for water extract and 75% ethanol extract of combined prescription of Danggui Buxue decoction, and 3,6 and 9 peaks respectively for the water extract, methanol extract and 75% ethanol extract of Rdix Anelica Snensis, and 7 peaks respectively for the water extract, methanol extract and 75% ethanol extract of radix astragli. A quality control method was also developedbased on the technique, which was able to simultaneously determine the concentrations of ferulic acid and liguistilide in extracts of combined prescription of Dnggui Buxue Decoction and Angelica sinensis by water and 75% ethanol, and its result show that the concentrations of ferulic acid in water extract and 75% ethanol extract of combined prescription of Danggui Buxue decoction is respectively 0.0743% and 0.0688%, and liguistilide, 0.0472% and 0.457%; the concentrations of ferulic acid in water extract and 75% ethanol extract of Angelica sinensis is respectively 0.0694% and 0.0691%,and liguistilide, 0.0781% and 0.455%.
关键词[WOS]: PREDICTION ;  DRUGS
语种: 英语
WOS记录号: WOS:000226245500007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138443
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.China Pharmaceut Univ, Dept Pharmacognosy, Key Lab Modern Tradit Chinese Med, Nanjing 210038, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China

Recommended Citation:
Sheng, LH,Li, RY,Li, P,et al. Analysis of biomembrane permeable compounds and quality control in combined prescription of traditional Chinese medicine by immobilized liposome chromatography[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2004,32(12):1595-1598.
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