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题名: Measurement of binding constant of host-guest interaction by capillary electrophoresis
作者: Zhu, XF;  Lin, BC
关键词: capillary electrophoresis ;  interaction ;  binding constant
刊名: CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
发表日期: 1999-12-01
卷: 27, 期:12, 页:1408-1411
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: The binding constant between beta-cyclodextrin (beta-CD) and the drug alprenolol was obtained by capillary electrophoresis, under the conditions of 100 mmol/L phosphate buffer, pH 2.5, 25 degrees C. Four methods, namely non-linear regression, double reciprocal, gamma-reciprocal and x-reciprocal were introduced to measure the binding constant, the values are 307.2 L/mol, 408.4 L/mol, 331.4 L/mol and 343.1 L/mol, respectively. The methods are applicable to measure the binding constant of Host-Guest interaction with 1:1 ratio.
关键词[WOS]: CYCLODEXTRINS ;  PHENOLS
语种: 英语
WOS记录号: WOS:000084530900010
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138647
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Acad Sinica, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Zhu, XF,Lin, BC. Measurement of binding constant of host-guest interaction by capillary electrophoresis[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,1999,27(12):1408-1411.
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