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题名: Improved mathematical model of APA microcapsules
作者: He, Y;  Xie, YB;  Wang, Y;  Liu, Q;  Ma, XJ
关键词: APA microcapsule ;  mathematical model ;  resistance coefficient ;  distribution coefficient
刊名: CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
发表日期: 2000-02-01
卷: 21, 期:2, 页:278-282
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: It is essential to investigate the diffusion characteristics of alginate-polylysine-alginate (APA) microcapsule system for its broad applications. An advanced mathematical model for protein diffusion in APA microcapsules is established, which presents the resistance coefficient of microcapsule membrane and distribution coefficient in microcapsule matrix. These two parameters as the important basis of optimizing preparation and directing application of microcapsule are determined by the measurement of the protein concentration in the extracapsular solution. With assistance of mathematical model, membrane diffusion characteristics affected by reaction time in membrane forming are analyzed: (1) microcapsule shows greater resistance constant and distribution constant to the diffusion of protein with greater molecular weight, (2) prologation reaction time results in increase in resistance constant and distribute constant of microcapsule.
语种: 英语
WOS记录号: WOS:000085504000030
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138780
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
He, Y,Xie, YB,Wang, Y,et al. Improved mathematical model of APA microcapsules[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2000,21(2):278-282.
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