DICP OpenIR
Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys
Xue, YL; Wang, ZF; Zhong, DG; Cui, X; Li, XJ; Ma, XJ; Wang, LN; Zhu, K; Sun, AM
KeywordParkinson's Disease Transplantation Dopamine Neostriatum Bovine Chromaffin Cells Encapsulation Microdialysis
Source PublicationARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY
2000
Volume28Issue:4Pages:337-345
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
WOS SubjectBiotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
WOS Research AreaBiotechnology & Applied Microbiology ; Engineering ; Materials Science
WOS KeywordTRANSPLANTATION
AbstractThis study examines the effects of xenografts of microencapsulated bovine chromaffin cells (BCCs) on the rotational behavior of hemiparkinsonian monkey recipients. In addition, it determines the content of monoamine neurotransmitters and their major metabolites in the neostriatum in hemiparkinsonian monkeys. The hemiparkinsonian model in monkeys was induced by a unilateral intracarotid injection of methyl-phenyl-tetrahydropyridine (MPTP). Unencapsulated BCCs, BCCs microencapsulated in alginate-polylysine-alginate (ALA) membranes as well as empty microencapsules were grafted into the neostriatum of the hemiparkinsonian monkeys.
Language英语
WOS IDWOS:000088182100006
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/138808
Collection中国科学院大连化学物理研究所
Affiliation1.PLA Gen Hosp, Inst Basic Med Sci, Beijing 100853, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem & Phys, Dalian 116033, Peoples R China
3.PLA Gen Hosp, Inst Neurol Dis, Beijing 100853, Peoples R China
4.Univ Toronto, Fac Med, Dept Physiol, Toronto, ON M5S 2A8, Canada
Recommended Citation
GB/T 7714
Xue, YL,Wang, ZF,Zhong, DG,et al. Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY,2000,28(4):337-345.
APA Xue, YL.,Wang, ZF.,Zhong, DG.,Cui, X.,Li, XJ.,...&Sun, AM.(2000).Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys.ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY,28(4),337-345.
MLA Xue, YL,et al."Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys".ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 28.4(2000):337-345.
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