DICP OpenIR
Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys
Xue, YL; Wang, ZF; Zhong, DG; Cui, X; Li, XJ; Ma, XJ; Wang, LN; Zhu, K; Sun, AM
关键词Parkinson's Disease Transplantation Dopamine Neostriatum Bovine Chromaffin Cells Encapsulation Microdialysis
刊名ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY
2000
28期:4页:337-345
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
类目[WOS]Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]TRANSPLANTATION
英文摘要This study examines the effects of xenografts of microencapsulated bovine chromaffin cells (BCCs) on the rotational behavior of hemiparkinsonian monkey recipients. In addition, it determines the content of monoamine neurotransmitters and their major metabolites in the neostriatum in hemiparkinsonian monkeys. The hemiparkinsonian model in monkeys was induced by a unilateral intracarotid injection of methyl-phenyl-tetrahydropyridine (MPTP). Unencapsulated BCCs, BCCs microencapsulated in alginate-polylysine-alginate (ALA) membranes as well as empty microencapsules were grafted into the neostriatum of the hemiparkinsonian monkeys.
语种英语
WOS记录号WOS:000088182100006
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文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/138808
专题中国科学院大连化学物理研究所
作者单位1.PLA Gen Hosp, Inst Basic Med Sci, Beijing 100853, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem & Phys, Dalian 116033, Peoples R China
3.PLA Gen Hosp, Inst Neurol Dis, Beijing 100853, Peoples R China
4.Univ Toronto, Fac Med, Dept Physiol, Toronto, ON M5S 2A8, Canada
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Xue, YL,Wang, ZF,Zhong, DG,et al. Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY,2000,28(4):337-345.
APA Xue, YL.,Wang, ZF.,Zhong, DG.,Cui, X.,Li, XJ.,...&Sun, AM.(2000).Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys.ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY,28(4),337-345.
MLA Xue, YL,et al."Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys".ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 28.4(2000):337-345.
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