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题名: Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys
作者: Xue, YL;  Wang, ZF;  Zhong, DG;  Cui, X;  Li, XJ;  Ma, XJ;  Wang, LN;  Zhu, K;  Sun, AM
关键词: Parkinson's disease ;  transplantation ;  dopamine ;  neostriatum ;  bovine chromaffin cells ;  encapsulation ;  microdialysis
刊名: ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY
发表日期: 2000
卷: 28, 期:4, 页:337-345
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Technology
类目[WOS]: Biotechnology & Applied Microbiology ;  Engineering, Biomedical ;  Materials Science, Biomaterials
研究领域[WOS]: Biotechnology & Applied Microbiology ;  Engineering ;  Materials Science
英文摘要: This study examines the effects of xenografts of microencapsulated bovine chromaffin cells (BCCs) on the rotational behavior of hemiparkinsonian monkey recipients. In addition, it determines the content of monoamine neurotransmitters and their major metabolites in the neostriatum in hemiparkinsonian monkeys. The hemiparkinsonian model in monkeys was induced by a unilateral intracarotid injection of methyl-phenyl-tetrahydropyridine (MPTP). Unencapsulated BCCs, BCCs microencapsulated in alginate-polylysine-alginate (ALA) membranes as well as empty microencapsules were grafted into the neostriatum of the hemiparkinsonian monkeys.
关键词[WOS]: TRANSPLANTATION
语种: 英语
WOS记录号: WOS:000088182100006
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138808
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.PLA Gen Hosp, Inst Basic Med Sci, Beijing 100853, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem & Phys, Dalian 116033, Peoples R China
3.PLA Gen Hosp, Inst Neurol Dis, Beijing 100853, Peoples R China
4.Univ Toronto, Fac Med, Dept Physiol, Toronto, ON M5S 2A8, Canada

Recommended Citation:
Xue, YL,Wang, ZF,Zhong, DG,et al. Xenotransplantation of microencapsulated bovine chromaffin into hemiparkinsonian monkeys[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY,2000,28(4):337-345.
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