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Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis
Zheng, XF; Wang, JY; Wang, Y; Gao, DB; Hu, JH
关键词Copper Ion Zinc Ion Superoxide Dismutase Serine Cobalt Interaction
刊名CHINESE JOURNAL OF CATALYSIS
2001-11-01
22期:6页:582-584
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences ; Technology
类目[WOS]Chemistry, Applied ; Chemistry, Physical ; Engineering, Chemical
研究领域[WOS]Chemistry ; Engineering
关键词[WOS]NMR
英文摘要The effect of changing the amount of externally added cobalt(II)-serine, an organic metal compound, and the pH value of the enzyme solution on the interaction of copper-zinc superoxide dismutase (Cu2Zn2SOD) with cobalt(II)-serine was studied by means of visible spectroscopy, inductively coupled plasma atomic emission spectrometry and measurement of enzyme activity. It was found that in aqueous solution, there exists a direct interaction of the metal ions of the active center in Cu(2)Zn2(S)OD with cobalt(II)-serine. As a result, part of the metal ions in the metalloenzyme were replaced by Co ion to form Co(II)-substituted derivatives of SOD and the catalytic activity of the enzyme decreased.
语种英语
WOS记录号WOS:000172730600020
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/138893
专题中国科学院大连化学物理研究所
作者单位1.Dalian Univ, Inst Bioengn, Dalian 116622, Peoples R China
2.Dalian Univ Technol, Coll Chem Engn, Dept Bioengn, Dalian 116012, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China
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GB/T 7714
Zheng, XF,Wang, JY,Wang, Y,et al. Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis[J]. CHINESE JOURNAL OF CATALYSIS,2001,22(6):582-584.
APA Zheng, XF,Wang, JY,Wang, Y,Gao, DB,&Hu, JH.(2001).Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis.CHINESE JOURNAL OF CATALYSIS,22(6),582-584.
MLA Zheng, XF,et al."Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis".CHINESE JOURNAL OF CATALYSIS 22.6(2001):582-584.
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