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题名: Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis
作者: Zheng, XF;  Wang, JY;  Wang, Y;  Gao, DB;  Hu, JH
关键词: copper ion ;  zinc ion ;  superoxide dismutase ;  serine ;  cobalt ;  interaction
刊名: CHINESE JOURNAL OF CATALYSIS
发表日期: 2001-11-01
卷: 22, 期:6, 页:582-584
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences ;  Technology
类目[WOS]: Chemistry, Applied ;  Chemistry, Physical ;  Engineering, Chemical
研究领域[WOS]: Chemistry ;  Engineering
英文摘要: The effect of changing the amount of externally added cobalt(II)-serine, an organic metal compound, and the pH value of the enzyme solution on the interaction of copper-zinc superoxide dismutase (Cu2Zn2SOD) with cobalt(II)-serine was studied by means of visible spectroscopy, inductively coupled plasma atomic emission spectrometry and measurement of enzyme activity. It was found that in aqueous solution, there exists a direct interaction of the metal ions of the active center in Cu(2)Zn2(S)OD with cobalt(II)-serine. As a result, part of the metal ions in the metalloenzyme were replaced by Co ion to form Co(II)-substituted derivatives of SOD and the catalytic activity of the enzyme decreased.
关键词[WOS]: NMR
语种: 英语
WOS记录号: WOS:000172730600020
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138893
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Univ, Inst Bioengn, Dalian 116622, Peoples R China
2.Dalian Univ Technol, Coll Chem Engn, Dept Bioengn, Dalian 116012, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China

Recommended Citation:
Zheng, XF,Wang, JY,Wang, Y,et al. Study on the interaction of copper-zinc superoxide dismutase with cobalt(II)-serine by spectral analysis[J]. CHINESE JOURNAL OF CATALYSIS,2001,22(6):582-584.
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