中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Enantiomer separation of mandelates and their analogs on cyclodextrin derivative chiral stationary phases by capillary GC
作者: Nie, MY;  Zhou, LM;  Wang, QH;  Zhu, DQ
刊名: ANALYTICAL SCIENCES
发表日期: 2001-10-01
卷: 17, 期:10, 页:1183-1187
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Enantiomer separation of mandelates and their analogs, which are important intermediates in asymmetric synthetic and pharmaceutical chemistry, was investigated by capillary gas chromatography using different cyclodextrin derivative chiral stationary phases (CD CSPs). The used cyclodextrin derivatives included permethylated beta -CD (PMBCD), permethylated gamma -CD, heptakis(2,6-di-O-butyl-3-O-butyryl)-beta -CD, heptakis(2,6-di-O-pentyl-3-O-acetyl)-beta -CD and heptakis(2,6-di-O-nonyl-3-O-trifluoroacetyl)-beta -CD (DNTBCD), respectively. Among all the CSPs used, PMBCD and DNTBCD exhibited the broadest and best enantioselectivity for all the racemates investigated. Some thermodynamic parameters were evaluated and an enthalpy-entropy compensation effect was observed in enantiomer separation processes of mandelates and their analogs. Based on thermodynamic data and molecular mechanics calculations, the chiral recognition mechanism of mandelate derivatives on CD CSPs is discussed.
关键词[WOS]: GAS-CHROMATOGRAPHY ;  RESOLUTION
语种: 英语
WOS记录号: WOS:000171855500009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/138957
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China

Recommended Citation:
Nie, MY,Zhou, LM,Wang, QH,et al. Enantiomer separation of mandelates and their analogs on cyclodextrin derivative chiral stationary phases by capillary GC[J]. ANALYTICAL SCIENCES,2001,17(10):1183-1187.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Nie, MY]'s Articles
 [Zhou, LM]'s Articles
 [Wang, QH]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Nie, MY]‘s Articles
 [Zhou, LM]‘s Articles
 [Wang, QH]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace