DICP OpenIR
Cellulose affinity membranes utilized for endotoxin removal
Wei, GL; Li, JH; Liu, XL; Shang, ZH; Yu, YN; Wang, JD; Pan, MC
KeywordAffinity Membrane Endotoxin Removal
Source PublicationCHINESE JOURNAL OF ANALYTICAL CHEMISTRY
2001-10-01
Volume29Issue:10Pages:1117-1120
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordADSORPTION
AbstractThis study mainly dealt with the preparation and application of affinity membranes utilized for endotoxin removal. Cellulose membrane was chosen as support and membranes with three kinds of affinity ligands, were prepared. They were chitosan affinity membrane (KFCC), hydrophobic and cationic charged membrane ( KFCG), and metal chelate affinity membrane (KFCM). All of these affinity membranes could be effectively used for removal of endotoxin in 0.9% NaCl solution, and the removal efficiencies were above 90%. In human serum albumin (HSA) solution, hydrophobic and cationic charged membrane and chitosan affinity membrane can also remove endotoxin efficiently, the removal efficiencies still were above 90% and the recoveries of HSA were over 95%. But metal chelate affinity membrane only can remove 83.3% endotoxin in HSA solution. The adsorption capacity of chitosan affinity membrane is more than 2.4 x 10(6) EU/g. Affinity membranes can treat several kinds of sample solutions and can be regenerated several times with suitable method.
Language英语
WOS IDWOS:000171887300001
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/138989
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China
2.Dalian Med Univ, Affiliated Hosp 1, Dalian 116011, Peoples R China
Recommended Citation
GB/T 7714
Wei, GL,Li, JH,Liu, XL,et al. Cellulose affinity membranes utilized for endotoxin removal[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2001,29(10):1117-1120.
APA Wei, GL.,Li, JH.,Liu, XL.,Shang, ZH.,Yu, YN.,...&Pan, MC.(2001).Cellulose affinity membranes utilized for endotoxin removal.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,29(10),1117-1120.
MLA Wei, GL,et al."Cellulose affinity membranes utilized for endotoxin removal".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 29.10(2001):1117-1120.
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