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题名: Analysis of 8-hydroxydeoxyguanosine in human urine by solid-phase extraction and derivatization gas chromatography
作者: Mei, SR;  Xu, GW;  Wu, CY
关键词: 8-hydroxydeoxyguanosine ;  gas chromatography ;  solid-phase extractions ;  derivatization ;  gas chromatography/mass spectrometry
刊名: CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
发表日期: 2001-12-01
卷: 29, 期:12, 页:1394-1397
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: A method for analysing 8-hydroxydeoxyguanosine (8OHdG) in human urine by solid-phase extraction and derivatization gas chromatography is described. The experimental conditions, especially the optimization of derivatization, were systematically studied. The 80HdG was identified by gas chromatography/mass spectrometry. The detection limit of this method is 4.56 pg/s, and the linear range is 0.2 similar to 100 mug. For the analysis of 80HdG in human urine, the RSD is less than 8.0% (n = 5).
关键词[WOS]: OXIDATIVE DNA-DAMAGE ;  8-HYDROXYGUANINE
语种: 英语
WOS记录号: WOS:000173025900007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/139027
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromotog Res & Anal Ctr, Dalian 116011, Peoples R China
2.Wuhan Univ, Coll Chem, Wuhan 430072, Peoples R China

Recommended Citation:
Mei, SR,Xu, GW,Wu, CY. Analysis of 8-hydroxydeoxyguanosine in human urine by solid-phase extraction and derivatization gas chromatography[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2001,29(12):1394-1397.
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