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Catalytic materials evaluated by adsorption and inactivation of parainfluenza virus and cytotoxicity of mammalian cells
Liu, ZM; Zhang, ZR; Xu, GW; Yang, L; Ma, L; Sun, CL; Xu, L; Qi, Y; Zhao, CX; Ming, PW; Chen, Y; Zheng, CL; Du, XF; Han, XW; Zhang, T; Huang, XY; Bao, XH; Liu, B; Liu, SX; Wang, AQ; Qu, ZP; Miao, SJ; Hu, G; Liu, Y
关键词Catalytic Materials Parainfluenza Virus Adsorption Inactivation Severe Acute Respiratory Syndrome
刊名CHINESE JOURNAL OF CATALYSIS
2003-05-01
24期:5页:323-327
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences ; Technology
类目[WOS]Chemistry, Applied ; Chemistry, Physical ; Engineering, Chemical
研究领域[WOS]Chemistry ; Engineering
关键词[WOS]ACUTE RESPIRATORY SYNDROME ; HONG-KONG ; CORONAVIRUS ; IDENTIFICATION
英文摘要A novel method for inactivating viruses based on adsorption and catalysis principles with the goal of developing non-specialized materials to filtrate, adsorb and catalyze viruses is proposed. These materials would be useful to more effectively control severe acute respiratory syndrome (SARS) in China. The parainfluenza virus (PIV), which is very similar to SARS coronavirus (SARS-CoV), was used in the adsorption and inactivation experiments, and the cytotoxic effects of the catalytic materials to mammalian cells were also investigated. The results of retardation and adsorption experiments on aerosol-type viruses are in agreement with those of DNA adsorption and capillary electrophoresis tests. Some materials could strongly adsorb the virus with 100% efficiency even after the third acute vibration in physiological saline. Some materials exhibit an interesting effect to inactivate the virus in eluates when the latter occurred positive in hemagglutination test and negative in detection of viable virus with inoculation to chicken embryo. These results suggested that the viruses were inactivated or decomposed by the catalytic effects. The cell virulence evaluation suggested that the very low toxicity of some materials is helpful for their application in protective garments. The materials with the highest performance will be tested with SARS-CoV, and the results are expected soon.
语种英语
WOS记录号WOS:000183665900004
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/139256
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China
2.Dalian Med Univ, Attached Teaching Hosp 2, Dalian 116023, Liaoning, Peoples R China
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GB/T 7714
Liu, ZM,Zhang, ZR,Xu, GW,et al. Catalytic materials evaluated by adsorption and inactivation of parainfluenza virus and cytotoxicity of mammalian cells[J]. CHINESE JOURNAL OF CATALYSIS,2003,24(5):323-327.
APA Liu, ZM.,Zhang, ZR.,Xu, GW.,Yang, L.,Ma, L.,...&Liu, Y.(2003).Catalytic materials evaluated by adsorption and inactivation of parainfluenza virus and cytotoxicity of mammalian cells.CHINESE JOURNAL OF CATALYSIS,24(5),323-327.
MLA Liu, ZM,et al."Catalytic materials evaluated by adsorption and inactivation of parainfluenza virus and cytotoxicity of mammalian cells".CHINESE JOURNAL OF CATALYSIS 24.5(2003):323-327.
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