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题名: Determination of multipeptide mixture by using CZE coupled with ESI-MS
作者: Liang, Z;  Zhang, WB;  Zhang, YK
关键词: capillary electrophoresis ;  peptide ;  mass spectrometry ;  sheath-liquid ;  electrospray ionization interface
刊名: CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
发表日期: 2004-03-10
卷: 25, 期:3, 页:448-450
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: CZE-ESI-MS is one of the most sensitive detection method and one of the potential method for protomics analysis. In this work, peptide mixture was separated and detected by using CZE-ESI-MS, and the influence of pH value of buffer and composition of sheath liquid on CE separation and MS detection was investigated. The method allows the detection limits up to 4.2-33 pg. The result of this method is better than that of CE-UV for the peptide analysis.
关键词[WOS]: IONIZATION MASS-SPECTROMETRY ;  CAPILLARY-ELECTROPHORESIS ;  LIQUID-CHROMATOGRAPHY ;  VOLATILE ELUENTS ;  PROTEIN ;  PEPTIDE ;  ELECTROLYTES ;  METABOLITES ;  SPECTRA
语种: 英语
WOS记录号: WOS:000220526000013
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/139283
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China

Recommended Citation:
Liang, Z,Zhang, WB,Zhang, YK. Determination of multipeptide mixture by using CZE coupled with ESI-MS[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2004,25(3):448-450.
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