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题名: Production and properties of an inhibitor of the Pseudomonas autoinducer by Pseudomonas aeruginosa
作者: Dong, WX;  Luo, F;  Du, YG;  Bai, XF;  Li, XZ
关键词: quorum sensing ;  autoinducer ;  PAI inhibitor ;  Pseudomonas aeruginosa ;  N-acylhomoserine lactone
刊名: CANADIAN JOURNAL OF MICROBIOLOGY
发表日期: 2005-09-01
DOI: 10.1139/W05-066
卷: 51, 期:9, 页:783-789
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Biochemistry & Molecular Biology ;  Biotechnology & Applied Microbiology ;  Immunology ;  Microbiology
研究领域[WOS]: Biochemistry & Molecular Biology ;  Biotechnology & Applied Microbiology ;  Immunology ;  Microbiology
英文摘要: An inhibitor was found in the culture fluid of Pseudomonas aeruginosa PAO1. which could inhibit the activity of the Pseudomonas autoinducer (PAI). The maximal inhibitory activity occurred in stationary phase culture supernatant. The PAI inhibitor did not influence the cell growth and the PAI production by P aeruginosa PAO1 when the PAI inhibitor was added into culture medium. The induced expression of lacZ in the reporter strain Agrobacterium tumefaciens NT1 was suppressed by this PAI inhibitor, whereas inhibition could be relieved by increasing the autoinducer concentration. The quorum sensing of P. aeruginoso was inhibited presumably by inhibiting the inducing activity of Pseudomonas autoinducer but not by inhibiting the production of Pseudonionas autoinducer. It was demonstrated that the structure of the PAI inhibitor was different from that of acyl-hornoserine lactones.
关键词[WOS]: TO-CELL COMMUNICATION ;  AGROBACTERIUM-TUMEFACIENS ;  VIRULENCE GENES ;  EXPRESSION ;  SIGNAL ;  LAS
语种: 英语
WOS记录号: WOS:000233824200008
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/139647
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Coll Light Ind, Dept Bio & Food Engn, Dalian 116034, Peoples R China
2.Dalian Inst Chem Phys, Dept Biotechnol, Dalian 116001, Peoples R China

Recommended Citation:
Dong, WX,Luo, F,Du, YG,et al. Production and properties of an inhibitor of the Pseudomonas autoinducer by Pseudomonas aeruginosa[J]. CANADIAN JOURNAL OF MICROBIOLOGY,2005,51(9):783-789.
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