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Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation
Xiong, JH; Weng, QF; Yuan, KL; Zhang, YK; Xu, GW
关键词Capillary Electrophoresis Optimization Genetic Algorithm Uniform Design Desirability Function
刊名CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
2005-06-01
33期:6页:755-758
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]BETA-CYCLODEXTRIN ; ZONE-ELECTROPHORESIS ; ACIDS
英文摘要Considering the complexity of chiral capillary electrophoresis separation mechanism, a multicriteria-decision-making optimization approach based on binary-coded genetic algorithm, which was independent of the statistic model used, was developed. According to the experiment parameters and their importances, the initial experiments were arranged using a uniform design. In order to achieve the simultaneous optimization of the two major electrophoretic performance goals for efficient and fast separations, the Derringer desirability functions were chosen as the optimization criteriaon. The selected parameters were encoded into binary bit strings, and then genetic algorithm calculations were performed to generate a new set of experimental conditions by the values of total desirability functions. This cycle process was repeated until a best separation criterion was reached. The method proposed was successfully applied to the enantioseparation of warfarin by chiral capillary electrophoresis.
语种英语
WOS记录号WOS:000230362500003
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被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/139663
专题中国科学院大连化学物理研究所
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China
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GB/T 7714
Xiong, JH,Weng, QF,Yuan, KL,et al. Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2005,33(6):755-758.
APA Xiong, JH,Weng, QF,Yuan, KL,Zhang, YK,&Xu, GW.(2005).Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,33(6),755-758.
MLA Xiong, JH,et al."Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 33.6(2005):755-758.
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