DICP OpenIR
Simultaneous determination of ten sulfa drugs in chicken meat by high performance liquid chromatography coulometric array detector
Li, SG; Zhao, JM; Wang, WX; Jin, Y; Du, YG
KeywordHigh Performance Liquid Chromatography Coulometric Array Sulfa Drug
Source PublicationCHINESE JOURNAL OF ANALYTICAL CHEMISTRY
2005-04-01
Volume33Issue:4Pages:442-446
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordAMPEROMETRIC DETECTION ; SULFONAMIDES ; HPLC ; DERIVATIZATION ; TISSUES
AbstractOne-step extraction and high performance liquid chromatography (HPLC) with coulometric porous graphite electrode array detector method have been developed for the determination of ten sulfa drugs residues in chicken meat. The extraction recoveries of the ten sulfa drugs are higher than 50% with mixture of acetonitrile and chloroform ( acetonitrile : chloroform is 10:1). The redox characteristics of the ten sulfa drugs on porous graphite electrode have been studied, and then the potential for detecting the sulfa drugs is fixed on 455,560,630,670 and 710 mV on electrodes in series. The ten analytes have been separated very well on Hypersil BDS C-18 column with mobile phases containing acetonitrile and 30 mmol/L NaH2PO4 ( pH 5), and with a linear gradient eluting program of acetonitrile from 8. 5% to 37.5% ( V/V) in 40 minutes. The contaminant from chicken meat does not affect the separation of the ten sulfa drugs. The limit of detection is 40 mu g/kg for SIA and 20 mu g/kg for SA, SDZ, SMR, SMZ, SPD, STZ, SMTZ, SCP, and SMX in chicken meat. There are good linear correlations between the peak areas and concentrations of the ten sulfa drugs, the linear range is 0. 1 similar to 2. 0 mg/L and the correlation coefficients are above 0. 99. The electrode recovery is simple and can realize on-line cleanout. This method using HPLC-coulometric array detector is reproducible, and sensitive enough for the determination of sulfa drugs in chicken meat. It is easy to perform.
Language英语
WOS IDWOS:000228870200002
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/139699
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Liaoning Normal Univ, Dalian 116029, Peoples R China
Recommended Citation
GB/T 7714
Li, SG,Zhao, JM,Wang, WX,et al. Simultaneous determination of ten sulfa drugs in chicken meat by high performance liquid chromatography coulometric array detector[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2005,33(4):442-446.
APA Li, SG,Zhao, JM,Wang, WX,Jin, Y,&Du, YG.(2005).Simultaneous determination of ten sulfa drugs in chicken meat by high performance liquid chromatography coulometric array detector.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,33(4),442-446.
MLA Li, SG,et al."Simultaneous determination of ten sulfa drugs in chicken meat by high performance liquid chromatography coulometric array detector".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 33.4(2005):442-446.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li, SG]'s Articles
[Zhao, JM]'s Articles
[Wang, WX]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li, SG]'s Articles
[Zhao, JM]'s Articles
[Wang, WX]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li, SG]'s Articles
[Zhao, JM]'s Articles
[Wang, WX]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.