中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis
作者: Liang, Aiye;  Du, Yuguang;  Wang, Keyi;  Lin, Bingcheng
关键词: capillary zone electrophoresis ;  granulocyte-macrophage colony-stimulating factor ;  heparin ;  interaction
刊名: JOURNAL OF SEPARATION SCIENCE
发表日期: 2006-07-01
DOI: 10.1002/jssc.200600084
卷: 29, 期:11, 页:1637-1641
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: The interactions between granulocyte-macrophage colony-stimulating factor (GMCSF) and heparin or low-molecular weight heparin (LMWH) were studied by CZE. It was found that GM-CSF could bind to both heparin and LMWH. The binding constants were calculated from Scatchard regression to be (6.5 +/- 0.8) x 10(5)/M and (11.2 +/- 0.7) x 10(5)/M, respectively. The specificity of the interaction between GM-CSF and heparin was also studied by employing another sulfated K carrageenan oligosaccharide as a control. Results showed that K carrageenan oligosaccharide could not interact with GM-CSF, indicating that GM-CSF could specifically interact with heparin.
关键词[WOS]: COLONY-STIMULATING FACTOR ;  FACTOR GM-CSF ;  ELECTROPHORESIS ;  BINDING ;  GLYCOSAMINOGLYCANS ;  AFFINITY ;  SULFATE
语种: 英语
WOS记录号: WOS:000239574100014
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/139942
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
3.Chinese Acad Sci, Shanghai Acad Life Sci, Inst Biochem & Cell Biol, Shanghai, Peoples R China

Recommended Citation:
Liang, Aiye,Du, Yuguang,Wang, Keyi,et al. Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis[J]. JOURNAL OF SEPARATION SCIENCE,2006,29(11):1637-1641.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Liang, Aiye]'s Articles
 [Du, Yuguang]'s Articles
 [Wang, Keyi]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Liang, Aiye]‘s Articles
 [Du, Yuguang]‘s Articles
 [Wang, Keyi]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace