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Multi-segment linear gradient optimization strategy based on resolution map in HPLC
Shan Yichu; Zhang Weibing; Seidel-Morgenstern, Andreas; Zhao Ruihuan; Zhang Yukui
关键词Optimization Multi-segment Linear Gradient Resolution Map Liquid Chromatography
刊名SCIENCE IN CHINA SERIES B-CHEMISTRY
2006-08-01
DOI10.1007/s11426-006-2004-y
49期:4页:315-325
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]PERFORMANCE LIQUID-CHROMATOGRAPHY ; COMPUTER-AIDED OPTIMIZATION ; ASSISTED RETENTION PREDICTION ; THIN-LAYER-CHROMATOGRAPHY ; COMPLEX SAMPLES ; OPTIMIZING TEMPERATURE ; EXCHANGE CHROMATOGRAPHY ; EXPERIMENTAL-DESIGN ; MOBILE-PHASE ; SEPARATION
英文摘要Based on the mechanism of chromatographic retention (the relationship between the retention of solute and the mobile phase conditions) and method of resolution map, several methods of optimizing multi-segment linear gradient elution conditions were proposed according to the different separation requirements of various samples. These methods were verified using literature data. Moreover, the advantages and disadvantages of these methods were compared. It was proved that the third method is a fast optimization method which is capable of separating all the components with relatively high resolution.
语种英语
WOS记录号WOS:000240332800004
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被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/140301
专题中国科学院大连化学物理研究所
作者单位1.Max Planck Inst Dynam Komplexer, Tech Syst, D-39106 Magdeburg, Germany
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
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GB/T 7714
Shan Yichu,Zhang Weibing,Seidel-Morgenstern, Andreas,et al. Multi-segment linear gradient optimization strategy based on resolution map in HPLC[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2006,49(4):315-325.
APA Shan Yichu,Zhang Weibing,Seidel-Morgenstern, Andreas,Zhao Ruihuan,&Zhang Yukui.(2006).Multi-segment linear gradient optimization strategy based on resolution map in HPLC.SCIENCE IN CHINA SERIES B-CHEMISTRY,49(4),315-325.
MLA Shan Yichu,et al."Multi-segment linear gradient optimization strategy based on resolution map in HPLC".SCIENCE IN CHINA SERIES B-CHEMISTRY 49.4(2006):315-325.
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