DICP OpenIR
Advances in hyphenated analytical techniques for shotgun proteome and peptidome analysis - A review
Hu, Lianghai; Ye, Mingliang; Jiang, Xiaogang; Feng, Shun; Zou, Hanfa
KeywordProteomics Peptidomics Hyphenated Techniques Multidimensional Separation Liquid Chromatography-mass Spectrometry Review
Source PublicationANALYTICA CHIMICA ACTA
2007-08-29
DOI10.1016/j.aca.2007.07.046
Volume598Issue:2Pages:193-204
Indexed BySCI
SubtypeReview
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordIONIZATION MASS-SPECTROMETRY ; PHASE LIQUID-CHROMATOGRAPHY ; ASSISTED-LASER-DESORPTION/IONIZATION ; MONOLITHIC CAPILLARY COLUMNS ; HUMAN PLASMA PROTEOME ; LC-ESI-MS/MS ; DYNAMIC-RANGE CHARACTERIZATION ; METAL AFFINITY-CHROMATOGRAPHY ; MULTIDIMENSIONAL SEPARATION ; NANOELECTROSPRAY IONIZATION
AbstractProteomics is defined as the analysis of part or all of the protein components of a complex biological system (a cell, organ or tissue) at a given moment. Due to the huge number of proteins encoded by the genome, novel analytical techniques must be developed to meet the need of large scale analysis. This has led to the hyphenation of multiple techniques to achieve this object. Here current status of the hyphenated analytical techniques of one-dimensional and multidimensional liquid chromatography-mass spectrometry for shotgun proteomic analysis is reviewed, and on-line techniques for automated sample preparation and injection are also covered. In addition, the hyphenated techniques for peptidome analysis are also covered. (c) 2007 Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000249483400002
Citation statistics
Cited Times:41[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/140632
Collection中国科学院大连化学物理研究所
AffiliationChinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Grad Sch, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Hu, Lianghai,Ye, Mingliang,Jiang, Xiaogang,et al. Advances in hyphenated analytical techniques for shotgun proteome and peptidome analysis - A review[J]. ANALYTICA CHIMICA ACTA,2007,598(2):193-204.
APA Hu, Lianghai,Ye, Mingliang,Jiang, Xiaogang,Feng, Shun,&Zou, Hanfa.(2007).Advances in hyphenated analytical techniques for shotgun proteome and peptidome analysis - A review.ANALYTICA CHIMICA ACTA,598(2),193-204.
MLA Hu, Lianghai,et al."Advances in hyphenated analytical techniques for shotgun proteome and peptidome analysis - A review".ANALYTICA CHIMICA ACTA 598.2(2007):193-204.
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