中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Synthesis of chiral cyclohexane-backbone P,N-ligands derived from pyridine and their applications in asymmetric catalysis
作者: Liu, Qi-Bin;  Zhou, Yong-Gui
刊名: TETRAHEDRON LETTERS
发表日期: 2007-03-19
DOI: 10.1016/j.tetlet.2007.01.123
卷: 48, 期:12, 页:2101-2104
收录类别: SCI ;  IC ;  CCR
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
英文摘要: P,N-ligands trans-4 and cis-5 with a cyclohexane backbone were easily synthesized. The key step was chiral resolution of ()-trans-2-pyridylcyclohexanols with DBTA. Enantiopure trans isomer was subjected to Mitsunobu reaction and deprotection to give the corresponding cis isomer. These ligands have been successfully used in asymmetric hydrogenation of arylalkenes with up to 93% ce using 5 and 90% ee using 4 and asymmetric allylic alkylations with up to 95% ee using 5 and 93% ee using 4. Trans and cis P,N-ligands 4 and 5 all gave the product with the same configuration. It was suggested that the absolute configuration of the product was controlled by the configuration of the stereogenic pyridyl-bearing carbon of the ligands. (c) 2007 Elsevier Ltd. All rights reserved.
关键词[WOS]: PHOSPHINITE-OXAZOLINE LIGANDS ;  ENANTIOSELECTIVE HYDROGENATION ;  DIASTEREOMERIC DERIVATIVES ;  IRIDIUM COMPLEXES ;  P,N LIGANDS ;  OLEFINS ;  ALCOHOLS ;  EXTRACTION ;  SEPARATION ;  RESOLUTION
语种: 英语
WOS记录号: WOS:000244995400011
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/140645
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China

Recommended Citation:
Liu, Qi-Bin,Zhou, Yong-Gui. Synthesis of chiral cyclohexane-backbone P,N-ligands derived from pyridine and their applications in asymmetric catalysis[J]. TETRAHEDRON LETTERS,2007,48(12):2101-2104.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Liu, Qi-Bin]'s Articles
 [Zhou, Yong-Gui]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Liu, Qi-Bin]‘s Articles
 [Zhou, Yong-Gui]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace