中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Rapid qualitative and quantitative analyses of flavanone aglycones in Fructus aurantii HPLC ion-trap MS
作者: Zhou, Da-yong;  Xu, Qing;  Xue, Xing-ya;  Zhang, Fei-fang;  Jing, Yu;  Liang, Xin-miao
关键词: characterization ;  flavanone aglycones ;  Fructus aurantii ;  LC-MSIMS ;  quantification
刊名: JOURNAL OF SEPARATION SCIENCE
发表日期: 2007-04-01
DOI: 10.1002/jssc.200600466
卷: 30, 期:6, 页:858-867
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: IT-MS operated in the positive mode Was applied for the rapid characterization/ quantification of the flavanones in extracts from Fructus aurantii. APCI-MS and CID MS/MS provide unequivocal molecular weight (MW) data of these compounds and useful information about their structures (diagnostic fragment ions). Main fragment pathways include neutral losses of H,O-2, C2H2O, and B-ring as well as a retro-Diels-Alder (RDA) fragment giving rise to [(1,3)A + H](+), [B-1,B-3 + H](+), and [B-1,B-4-H-2 + H](+) ions, which form the characteristic MS/MS "fingerprint" of flavanone aglycones. When screening extracts of F. aurantii for flavanone aglycones, eight target compounds were characterized using this fingerprint. Meanwhile, ESI-MS in full-scan mode was developed and validated for the quantification of the main flavanone aglycones in F. aurantii. This method is simple, accurate, fast and requires only 16 min per sample for direct detection and quantification of naringenin and hesperetin. All the results and these characteristic fragments showed that the IT-MS is a powerful tool for the structural characterization and quantitative determination of flavanone aglycones.
关键词[WOS]: IONIZATION MASS-SPECTROMETRY ;  FLAVONOID-O-GLYCOSIDES ;  ELECTROSPRAY-IONIZATION ;  LIQUID-CHROMATOGRAPHY ;  METHOXYLATED FLAVONOIDS ;  METAL COMPLEXATION ;  RATS PLASMA ;  DIFFERENTIATION ;  FRAGMENTATION ;  GLYCOSYLATION
语种: 英语
WOS记录号: WOS:000246348000011
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/140743
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Zhou, Da-yong,Xu, Qing,Xue, Xing-ya,et al. Rapid qualitative and quantitative analyses of flavanone aglycones in Fructus aurantii HPLC ion-trap MS[J]. JOURNAL OF SEPARATION SCIENCE,2007,30(6):858-867.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Zhou, Da-yong]'s Articles
 [Xu, Qing]'s Articles
 [Xue, Xing-ya]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Zhou, Da-yong]‘s Articles
 [Xu, Qing]‘s Articles
 [Xue, Xing-ya]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace