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Preparation of novel beta-cyclodextrin chiral stationary phase based on click chemistry
Zhang, Yongping1; Guo, Zhimou3; Ye, Jinxing1; Xu, Qing3; Liang, Xinmiao1,3; Lei, Aiwen2
KeywordBeta-cyclodextrin Chiral Stationary Phases Click Chemistry Chiral Separation
Source PublicationJOURNAL OF CHROMATOGRAPHY A
2008-05-16
DOI10.1016/j.chroma.2007.11.018
Volume1191Issue:1-2Pages:188-192
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordPERFORMANCE LIQUID-CHROMATOGRAPHY ; BONDED SILICA-GEL ; RETENTION BEHAVIOR ; AROMATIC-COMPOUNDS ; HPLC ; SEPARATION ; ENANTIOSEPARATION ; DERIVATIVES ; FACILE ; IMMOBILIZATION
AbstractA facile strategy based on click chemistry for preparation of the structurally well-defined native beta-cyclodextrin (beta-CD) based chiral stationary phase (CSP) was proposed. The beta-CD CSP was evaluated by enatioseparation of benzoin, trans-stilbene oxide, Troger's base, bendroflumethiazide, ketoprofen, chlorthalidone, three flavanone compounds and two beta-adrenergic blocking agents under reversed phase high performance liquid chromatography. The chromatographic results demonstrate the chiral separation ability of click beta-CD CSP and illustrate the usefulness of click chemistry in the preparation of beta-CD based CSP. (c) 2007 Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000256326400021
Citation statistics
Cited Times:81[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/140953
Collection中国科学院大连化学物理研究所
Affiliation1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
2.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Yongping,Guo, Zhimou,Ye, Jinxing,et al. Preparation of novel beta-cyclodextrin chiral stationary phase based on click chemistry[J]. JOURNAL OF CHROMATOGRAPHY A,2008,1191(1-2):188-192.
APA Zhang, Yongping,Guo, Zhimou,Ye, Jinxing,Xu, Qing,Liang, Xinmiao,&Lei, Aiwen.(2008).Preparation of novel beta-cyclodextrin chiral stationary phase based on click chemistry.JOURNAL OF CHROMATOGRAPHY A,1191(1-2),188-192.
MLA Zhang, Yongping,et al."Preparation of novel beta-cyclodextrin chiral stationary phase based on click chemistry".JOURNAL OF CHROMATOGRAPHY A 1191.1-2(2008):188-192.
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