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题名: Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance
作者: Li, Hui Hui1;  Yuan, Gu1
关键词: G-quadruplex ;  HIV-1 integrase inhibitor ;  Nuclear magnetic resonance
刊名: CHINESE CHEMICAL LETTERS
发表日期: 2008-09-01
DOI: 10.1016/j.cclet.2008.06.010
卷: 19, 期:9, 页:1108-1110
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: In this research, an unusually dimeric G-quadruplex of d(GGGTGGGTGGGTGGGT) (S1), the potent nanomolar HIV-1 integrase inhibitor, was detected by nuclear magnetic resonance (NMR). This result has been confirmed by electrospray ionization mass spectrometry (ESI-MS) and circular dichroism (CD). (c) 2008 Gu Yuan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
关键词[WOS]: SEQUENCE ;  DNA
语种: 英语
WOS记录号: WOS:000263669100026
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141147
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Dept Chem Biol,Coll Chem & Mol Engn,Minist Educ, Beijing 100871, Peoples R China

Recommended Citation:
Li, Hui Hui,Yuan, Gu. Investigation of formation of dimeric G-quadruplex of HIV-1 integrase inhibitor by nuclear magnetic resonance[J]. CHINESE CHEMICAL LETTERS,2008,19(9):1108-1110.
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