中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Unexpected influence and its origin in rationally tuning the electronic effect of catalysts in the asymmetric borane reduction of ketones
作者: Du, Juanjuan1;  Li, Zhiyi1;  Du, Da-Ming1;  Xu, Jiaxi1, 2
关键词: asymmetric reduction ;  borane ;  electronic effect ;  enantioselectivity ;  ketone
刊名: JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
发表日期: 2008-04-02
DOI: 10.1016/j.molcata.2008.01.018
卷: 284, 期:1-2, 页:40-45
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Physical
研究领域[WOS]: Chemistry
英文摘要: Rationally tuning the electronic effect of catalysts is one of the most important strategies to improve stereoselectivity in asymmetric catalysis. (S)-2-aryl-3,1,2-oxazaborobicyclo[3.3.0] octanes, which can be considered as electronically tuned (S)-2-phenyl-3,1,2-oxazaborobicyclo[3.3.0] octane, were prepared and evaluated in the asymmetric borane reduction of ketones. An unexpected influence of the electronic effect of catalysts on the enantioselectivity was observed and attributed to the catalyst dimerization that was further confirmed experimentally. The unsuccessful tuning is accounted for by assuming that hydride transfer in the catalytic cycle is the rate-determining step in the reduction. catalyzed by B-aryl catalysts. (C) 2008 Published by Elsevier B.V.
关键词[WOS]: HIGH ENANTIOSELECTIVITY ;  PI-STACKING ;  PROCHIRAL KETONES ;  MECHANISM ;  LIGANDS ;  DIHYDROXYLATION ;  HYDROGENATION ;  AZIRIDINATION ;  ACETOPHENONE ;  SUBSTITUENTS
语种: 英语
WOS记录号: WOS:000255189100006
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141150
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, BNLMS, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Coll Chem & Mol Engn, Beijing 100871, Peoples R China
2.Beijing Univ Chem Technol, Coll Sci, Beijing 100029, Peoples R China

Recommended Citation:
Du, Juanjuan,Li, Zhiyi,Du, Da-Ming,et al. Unexpected influence and its origin in rationally tuning the electronic effect of catalysts in the asymmetric borane reduction of ketones[J]. JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL,2008,284(1-2):40-45.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Du, Juanjuan]'s Articles
 [Li, Zhiyi]'s Articles
 [Du, Da-Ming]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Du, Juanjuan]‘s Articles
 [Li, Zhiyi]‘s Articles
 [Du, Da-Ming]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace