中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Protein-responsive imprinted polymers with specific shrinking and rebinding
作者: Chen, Zhiyong1;  Hua, Zhendong1;  Xu, Li1;  Huang, Yong1;  Zhao, Meiping1;  Li, Yuanzong1
关键词: molecularly imprinted polymer (MIP) ;  hydrogel ;  specific shrinking ;  protein recognition
刊名: JOURNAL OF MOLECULAR RECOGNITION
发表日期: 2008
DOI: 10.1002/jmr.870
卷: 21, 期:1, 页:71-77
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Biochemistry & Molecular Biology ;  Biophysics
研究领域[WOS]: Biochemistry & Molecular Biology ;  Biophysics
英文摘要: Stimuli-responsive protein imprinted polymers were obtained via a combination of molecular imprinting and reversible stimuli-responsive polymer using lysozyme or cytochrome c as template, N-isopropylacrylamide (NIPA) as major monomer, methacrylic acid (MAA) and acrylamide (AAm) as functional co-monomers, and N,N-methylenebisacrylamide (MBAAm) as crosslinker. The molecularly imprinted polymers (MIPs) can respond not only to external stimuli such as temperature and salt concentration, but also to the corresponding template protein with significant specific volume shrinking. This specific shrinking behavior was attributed to the synergistic effect of multiple-site weak interactions (electrostatic force, hydrogen bonding and hydrophobic interaction) and the cavity effect. The MIPs showed highly selective adsorption of template proteins with specific shrinking compared with the non-imprinted polymers. The results indicated that the MIPs seemed to change shape to accommodate the conformation of the template protein leading to the formation of a shape complementary cavity. Copyright (c) 2008 John Wiley & Sons, Ltd.
关键词[WOS]: ARTIFICIAL ANTIBODIES ;  HYDROGELS ;  RECOGNITION ;  GELS ;  LYSOZYME ;  MOLECULES ;  RELEASE ;  BEADS
语种: 英语
WOS记录号: WOS:000253689800008
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141226
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, BNLMS, Beijing 100871, Peoples R China

Recommended Citation:
Chen, Zhiyong,Hua, Zhendong,Xu, Li,et al. Protein-responsive imprinted polymers with specific shrinking and rebinding[J]. JOURNAL OF MOLECULAR RECOGNITION,2008,21(1):71-77.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Chen, Zhiyong]'s Articles
 [Hua, Zhendong]'s Articles
 [Xu, Li]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Chen, Zhiyong]‘s Articles
 [Hua, Zhendong]‘s Articles
 [Xu, Li]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace