DICP OpenIR
Protein-responsive imprinted polymers with specific shrinking and rebinding
Chen, Zhiyong; Hua, Zhendong; Xu, Li; Huang, Yong; Zhao, Meiping; Li, Yuanzong
关键词Molecularly Imprinted Polymer (Mip) Hydrogel Specific Shrinking Protein Recognition
刊名JOURNAL OF MOLECULAR RECOGNITION
2008
DOI10.1002/jmr.870
21期:1页:71-77
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]ARTIFICIAL ANTIBODIES ; HYDROGELS ; RECOGNITION ; GELS ; LYSOZYME ; MOLECULES ; RELEASE ; BEADS
英文摘要Stimuli-responsive protein imprinted polymers were obtained via a combination of molecular imprinting and reversible stimuli-responsive polymer using lysozyme or cytochrome c as template, N-isopropylacrylamide (NIPA) as major monomer, methacrylic acid (MAA) and acrylamide (AAm) as functional co-monomers, and N,N-methylenebisacrylamide (MBAAm) as crosslinker. The molecularly imprinted polymers (MIPs) can respond not only to external stimuli such as temperature and salt concentration, but also to the corresponding template protein with significant specific volume shrinking. This specific shrinking behavior was attributed to the synergistic effect of multiple-site weak interactions (electrostatic force, hydrogen bonding and hydrophobic interaction) and the cavity effect. The MIPs showed highly selective adsorption of template proteins with specific shrinking compared with the non-imprinted polymers. The results indicated that the MIPs seemed to change shape to accommodate the conformation of the template protein leading to the formation of a shape complementary cavity. Copyright (c) 2008 John Wiley & Sons, Ltd.
语种英语
WOS记录号WOS:000253689800008
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/141226
专题中国科学院大连化学物理研究所
作者单位Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, BNLMS, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Chen, Zhiyong,Hua, Zhendong,Xu, Li,et al. Protein-responsive imprinted polymers with specific shrinking and rebinding[J]. JOURNAL OF MOLECULAR RECOGNITION,2008,21(1):71-77.
APA Chen, Zhiyong,Hua, Zhendong,Xu, Li,Huang, Yong,Zhao, Meiping,&Li, Yuanzong.(2008).Protein-responsive imprinted polymers with specific shrinking and rebinding.JOURNAL OF MOLECULAR RECOGNITION,21(1),71-77.
MLA Chen, Zhiyong,et al."Protein-responsive imprinted polymers with specific shrinking and rebinding".JOURNAL OF MOLECULAR RECOGNITION 21.1(2008):71-77.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, Zhiyong]的文章
[Hua, Zhendong]的文章
[Xu, Li]的文章
百度学术
百度学术中相似的文章
[Chen, Zhiyong]的文章
[Hua, Zhendong]的文章
[Xu, Li]的文章
必应学术
必应学术中相似的文章
[Chen, Zhiyong]的文章
[Hua, Zhendong]的文章
[Xu, Li]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。