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题名: Preliminary Recognition of c-Myc Gene Protein Using an Optical Biosensor with Gold Colloid Nanoparticles Based on Localized Surface Plasmon Resonance
作者: Cao, Zhong1;  Gong, Fu-Chun1;  Tu, Ming1;  Zeng, Meng-Xue1;  Huang, Xi-Xi1;  Zhang, Ling1;  Tan, Shu-Zhen1;  Sun, Li-Xian2;  Gu, Ning3
关键词: Gold nanoparticles ;  localized surface plasmon resonance ;  oncogene protein ;  optical nanobiosensor ;  pCMV-Myc
刊名: ANALYTICAL LETTERS
发表日期: 2009
DOI: 10.1080/00032710903082820
卷: 42, 期:17, 页:2820-2837
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: The gold colloidal nanoparticles with a diameter of 24 +/- 0.2nm were prepared, characterized by ultraviolet-visible (UV-vis), transmission electron microscopy (TEM), and cyclic voltammetry, and assembled on a gold plate substrate for constructing an optical nanobiosensor. The nanosensor exhibited distinct optical properties of localized surface plasmon resonance (LSPR), which could be used for recognition of oncogene biomolecules such as the c-Myc (3C7) antibody protein. The LSPR nanobiosensor has also been successfully applied to determination of a pCMV-Myc mammalian expression vector, one kind of DNA plasmids with a linear response range of 6.2-20.0ng/mu L and a detection limit of 2.4ng/mu L.
关键词[WOS]: ENHANCED RAMAN-SCATTERING ;  MICROFLUIDIC BEADS ARRAY ;  SILVER NANOPARTICLES ;  G-QUADRUPLEX ;  MOLECULES ;  ONCOGENE ;  SENSOR ;  ASSAY ;  METALLOPORPHYRIN ;  SPECTROSCOPY
语种: 英语
WOS记录号: WOS:000271507500007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141338
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Mat & Thermochem Lab, Dalian, Peoples R China
3.Southeast Univ, Sch Biol Sci & Med Engn, Natl Lab Mol & Biomol Elect, Jiangsu Lab Biomat & Devices, Nanjing, Peoples R China

Recommended Citation:
Cao, Zhong,Gong, Fu-Chun,Tu, Ming,et al. Preliminary Recognition of c-Myc Gene Protein Using an Optical Biosensor with Gold Colloid Nanoparticles Based on Localized Surface Plasmon Resonance[J]. ANALYTICAL LETTERS,2009,42(17):2820-2837.
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