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题名: Low Molecular Weight and Oligomeric Chitosans and Their Bioactivities
作者: Yin, Heng1;  Du, Yuguang1;  Zhang, Junzeng2
关键词: Low molecular weight chitosan (LMWC) ;  chitosan oligosaccharide (COS) ;  preparation ;  analytical method ;  bioactivity
刊名: CURRENT TOPICS IN MEDICINAL CHEMISTRY
发表日期: 2009-11-01
卷: 9, 期:16, 页:1546-1559
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Chemistry, Medicinal
研究领域[WOS]: Pharmacology & Pharmacy
英文摘要: Chitosan is one of the most abundant marine-based biopolymers. Low molecular weight and oligomeric chitosans are water-soluble hydrolysates of chitosan. They have been shown to have a wide range of biological activities and industrial applications. In particular, low molecular weight and oligomeric chitosans have been reported to have the health benefits such as immunity regulation, anti-tumor, liver protection, blood lipids lowering, anti-diabetic, antioxidant and anti-obesity. In this paper, the preparation and analytical methods, and bioactivities of these low molecular weight and oligomeric chitosans were reviewed, with the latest progresses introduced and discussed.
关键词[WOS]: WATER-SOLUBLE CHITOSAN ;  BETA-D-GLUCOSAMINIDASE ;  RADICAL SCAVENGING ACTIVITY ;  HIGH-INTENSITY ULTRASOUND ;  ACE INHIBITORY-ACTIVITY ;  PANCREATIC-ISLET CELLS ;  INDUCED DIABETIC-RATS ;  IN-VITRO ;  ANTIOXIDANT ACTIVITY ;  HETERO-CHITOOLIGOSACCHARIDES
语种: 英语
WOS记录号: WOS:000272785100005
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141391
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Liaoning Prov Key Lab Carbohydrates, Dalian 116023, Liaoning, Peoples R China
2.Natl Res Council Canada, Inst Nutrisci & Hlth, Charlottetown, PE C1A 4P3, Canada

Recommended Citation:
Yin, Heng,Du, Yuguang,Zhang, Junzeng. Low Molecular Weight and Oligomeric Chitosans and Their Bioactivities[J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY,2009,9(16):1546-1559.
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