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题名: Characterization and biodegradation of chitosan-alginate polyelectrolyte complexes
作者: Li, Xiaoxia1, 2;  Xie, Hongguo1, 2;  Lin, Junzhang1, 2;  Xie, Weiyang1;  Ma, Xiaojun1
关键词: Chitosan ;  Alginate ;  Polyelectrolyte complex ;  Biodegradation ;  Lysozyme
刊名: POLYMER DEGRADATION AND STABILITY
发表日期: 2009
DOI: 10.1016/j.polymdegradstab.2008.10.017
卷: 94, 期:1, 页:1-6
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Polymer Science
研究领域[WOS]: Polymer Science
英文摘要: Polyelectrolyte complexes (PECs) have been the focus of an expanding number of studies for their wide use. This study investigated the characteristics and biodegradation of chitosan-alginate PECs prepared by freeze-drying a precipitate from sufficient mixtures of the two polymers. The analyses of X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and differential scanning calorimetry (DSC) suggested that the partial protonated amine groups of chitosan reacted with the carboxylate groups of alginate and thus strong PECs were formed. After incubating in lysozyme solution, the PECs showed high ability of enzyme adsorption, and low degradation rate in spite of different degrees of deacetylation of chitosan, due to the strong interaction between chitosan and alginate and the hindrance of closely adsorbed lysozyme. (C) 2008 Elsevier Ltd. All rights reserved.
关键词[WOS]: N-ACETYLATED CHITOSANS ;  IN-VITRO ;  PROTEIN ADSORPTION ;  SODIUM ALGINATE ;  DEGRADATION ;  SCAFFOLDS ;  BIOMATERIALS ;  HYDROGELS ;  LYSOZYME ;  DELIVERY
语种: 英语
WOS记录号: WOS:000262954800001
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141440
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

Recommended Citation:
Li, Xiaoxia,Xie, Hongguo,Lin, Junzhang,et al. Characterization and biodegradation of chitosan-alginate polyelectrolyte complexes[J]. POLYMER DEGRADATION AND STABILITY,2009,94(1):1-6.
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