DICP OpenIR
"One-Pot" Process for Fabrication of Organic-Silica Hybrid Monolithic Capillary Columns Using Organic Monomer and Alkoxysilane
Wu, Minghuo1; Wu, Ren'an1; Wang, Fangjun1; Ren, Lianbing2; Dong, Jing1; Liu, Zhen2; Zou, Hanfa1
刊名ANALYTICAL CHEMISTRY
2009-05-01
DOI10.1021/ac9000749
81期:9页:3529-3536
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]PERFORMANCE LIQUID-CHROMATOGRAPHY ; STATIONARY PHASES ; PROTEOME ANALYSIS ; HIGH-EFFICIENCY ; ELECTROCHROMATOGRAPHY ; IMPROVEMENT ; SEPARATION ; FLOW
英文摘要A "one-pot" process for the preparation of organic-silica hybrid capillary monolithic columns by concurrently using organic monomers and alkoxysilanes was described. In this process, the hydrolyzed alkoxysilanes of tetramethoxysilane (TMOS) and vinyltrimethoxysilane (VTMS) as precursors for the synthesis of a silica.-based monolith using the sol-gel method and the organic monomer (allyldimethyldodecylammonium bromide (ADDAB) or acrylamide (AA)) with vinyl groups for free radical polymerization along with the initiator of azobisisobutyronitrile (AIBN) were concurrently introduced into a pretreated capillary; after that, the polycondensation of alkoxysilanes and the copolymerization of organic monomers and as-precondensed siloxanes were subsequently carried out within the confines of a capillary at the proper reaction conditions. Two types of organic-silica hybrid capillary monolithic columns with hydrophobic and hydrophilic properties have been fabricated, respectively, by this "onepot" process using two different organic monomers of ADDAB and AA. The morphologies of the synthesized organic-silica hybrid monolithic columns were characterized by scanning electron microscopy (SEIM). The performances of these organic-silica monolithic columns were investigated by capillary electrochromatography (CEC). The retention behaviors of the neutral and polar compounds on the resulting hydrophobic and hydrophilic organic-silica hybrid monolithic columns confirmed the successful incorporation of organic monomers in the silica monolithic matrix. In addition, the JWDA-silica hybrid capillary monolithic column was also applied in the analysis of tryptic-digests of bovine serum albumin (BSA) and mouse liver extract by microliquid chromatography-tandem mass spectrometry (mu LC-MS/MS) for demonstrating its potential in proteome analysis.
语种英语
WOS记录号WOS:000265632400045
引用统计
被引频次:108[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/141457
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
2.Nanjing Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China
推荐引用方式
GB/T 7714
Wu, Minghuo,Wu, Ren'an,Wang, Fangjun,et al. "One-Pot" Process for Fabrication of Organic-Silica Hybrid Monolithic Capillary Columns Using Organic Monomer and Alkoxysilane[J]. ANALYTICAL CHEMISTRY,2009,81(9):3529-3536.
APA Wu, Minghuo.,Wu, Ren'an.,Wang, Fangjun.,Ren, Lianbing.,Dong, Jing.,...&Zou, Hanfa.(2009)."One-Pot" Process for Fabrication of Organic-Silica Hybrid Monolithic Capillary Columns Using Organic Monomer and Alkoxysilane.ANALYTICAL CHEMISTRY,81(9),3529-3536.
MLA Wu, Minghuo,et al.""One-Pot" Process for Fabrication of Organic-Silica Hybrid Monolithic Capillary Columns Using Organic Monomer and Alkoxysilane".ANALYTICAL CHEMISTRY 81.9(2009):3529-3536.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wu, Minghuo]的文章
[Wu, Ren'an]的文章
[Wang, Fangjun]的文章
百度学术
百度学术中相似的文章
[Wu, Minghuo]的文章
[Wu, Ren'an]的文章
[Wang, Fangjun]的文章
必应学术
必应学术中相似的文章
[Wu, Minghuo]的文章
[Wu, Ren'an]的文章
[Wang, Fangjun]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。