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Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene
Li, Huihui1,2; Yuan, Gu1
刊名RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2010-07-01
DOI10.1002/rcm.4613
24期:14页:2030-2034
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
关键词[WOS]I-MOTIF STRUCTURES ; C-MYC PROMOTER ; TUMOR ANGIOGENESIS ; INTERACTIVE AGENTS ; FACTOR EXPRESSION ; FORMING REGION ; SMALL-MOLECULE ; CANCER CELLS ; DNA ; TRANSCRIPTION
英文摘要The formation of the G-quadruplex of the vascular endothelial growth factor (VEGF) gene was probed by electrospray ionization mass spectrometry (ESI-MS). It found that cations (K(+) and NH(4)(+)), CH(3)OH and pH influence significantly the formation of the G-quadruplex structure. Additionally, a perylene derivative (P3) and polydatin (P4) have shown to be potential G-quadruplex binding agents with structurally specific recognition. Copyright (C) 2010 John Wiley & Sons, Ltd.
语种英语
WOS记录号WOS:000280117200013
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被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/141740
专题中国科学院大连化学物理研究所
作者单位1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Dept Chem Biol,Coll Chem & Mol Engn, Beijing 100871, Peoples R China
2.Nanjing Normal Univ, Jiangsu Key Lab Biofunct Mat, Sch Chem & Environm Sci, Nanjing 210097, Peoples R China
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Li, Huihui,Yuan, Gu. Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2010,24(14):2030-2034.
APA Li, Huihui,&Yuan, Gu.(2010).Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,24(14),2030-2034.
MLA Li, Huihui,et al."Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 24.14(2010):2030-2034.
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