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题名: New Developments of Quantitative Mass Spectrometry-based Proteomics
作者: Zhu Jin-Lei1;  Zhang Kai1;  He Xi-Wen1;  Zhang Yu-Kui1, 2
关键词: Mass spectrometry ;  Proteomics ;  Quantitative ;  Isotope labeling ;  Review
刊名: CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
发表日期: 2010-03-01
DOI: 10.1016/S1872-2040(09)60032-3
卷: 38, 期:3, 页:434-441
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Mass spectrometry has become a powerful technology for proteome analysis. It would be highly desirable to obtain an exact quantitative value and the dynamic data of each protein in a system for providing important information to study protein function, to reveal the biological process and to discover protein biomarker and drug target. In this paper, the developments of quantitative mass spectrometry-based proteomics on strategy, method and application in recent years with further addressed characteristics and potentialities in protein analysis are discussed.
关键词[WOS]: CODED AFFINITY TAGS ;  MULTIPLEXED ABSOLUTE QUANTIFICATION ;  CONCATENATED SIGNATURE PEPTIDES ;  STATE PROTEIN-PHOSPHORYLATION ;  SITE-SPECIFIC PHOSPHORYLATION ;  GROWTH-FACTOR RECEPTOR ;  CELL-CULTURE SILAC ;  AMINO-ACIDS ;  ION-TRAP ;  2-DIMENSIONAL ELECTROPHORESIS
语种: 英语
WOS记录号: WOS:000276536700029
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/141759
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China

Recommended Citation:
Zhu Jin-Lei,Zhang Kai,He Xi-Wen,et al. New Developments of Quantitative Mass Spectrometry-based Proteomics[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2010,38(3):434-441.
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