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Inhibitory study of two cephalosporins on E. coli by microcalorimetry
Yang, L. N.1,2; Sun, Li Xian1; Xu, Fen3; Zhang, J.1; Zhao, J. N.1; Zhao, Z. B.4; Song, C. G.5; Wu, R. H.5; Ozao, Riko6
关键词Cefpiramide Ceftizoxime Sodium Cephalosporins E. Coli Dh5 Alpha Metabolism Inhibition Microcalorimetry
刊名JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
2010-05-01
DOI10.1007/s10973-009-0222-1
100期:2页:589-592
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical ; Chemistry, Physical
研究领域[WOS]Chemistry
关键词[WOS]TOXIC ACTION ; GROWTH ; METABOLISM ; TISSUE ; ANTIBIOTICS ; CEFPIRAMIDE ; DH5-ALPHA ; CR(VI)
英文摘要The microcalorimetric method has been used to study the effects of cefpiramide and ceftizoxime sodium on the E. coli growth. The results revealed that these two cephalosporins may alter the metabolic way of the E. coli. Moreover, the lethal doses of cefpiramide and ceftizoxime sodium are 2.000 and 0.2000 mu g mL(-1), respectively. Combining with the relationships between growth rate constant (k), the maximum power output (P (m) ), the time corresponding to the maximum power output (t (m) ) and cephalosporins concentration (C), one can draw the conclusion that the ceftizoxime sodium has a stronger inhibition effects on the growth of E. coli than that of cefpiramide and they both have the possibility to induce the drug fever.
语种英语
WOS记录号WOS:000276771600028
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/141981
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Mat & Thermochem Lab, Dalian 116023, Peoples R China
2.Zunyi Normal Coll, Dept Chem, Zunyi 563002, Peoples R China
3.Liaoning Normal Univ, Coll Chem & Chem Engn, Dalian 116029, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
5.Dalian Inst Drug Detect, Dalian 116021, Peoples R China
6.Sony Corp, Inst Higher Educ, Kanagawa 2438501, Japan
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Yang, L. N.,Sun, Li Xian,Xu, Fen,et al. Inhibitory study of two cephalosporins on E. coli by microcalorimetry[J]. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,2010,100(2):589-592.
APA Yang, L. N..,Sun, Li Xian.,Xu, Fen.,Zhang, J..,Zhao, J. N..,...&Ozao, Riko.(2010).Inhibitory study of two cephalosporins on E. coli by microcalorimetry.JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,100(2),589-592.
MLA Yang, L. N.,et al."Inhibitory study of two cephalosporins on E. coli by microcalorimetry".JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 100.2(2010):589-592.
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