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Inhibitory study of two cephalosporins on E. coli by microcalorimetry
Yang, L. N.1,2; Sun, Li Xian1; Xu, Fen3; Zhang, J.1; Zhao, J. N.1; Zhao, Z. B.4; Song, C. G.5; Wu, R. H.5; Ozao, Riko6
KeywordCefpiramide Ceftizoxime Sodium Cephalosporins E. Coli Dh5 Alpha Metabolism Inhibition Microcalorimetry
Source PublicationJOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
2010-05-01
DOI10.1007/s10973-009-0222-1
Volume100Issue:2Pages:589-592
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical ; Chemistry, Physical
WOS Research AreaChemistry
WOS KeywordTOXIC ACTION ; GROWTH ; METABOLISM ; TISSUE ; ANTIBIOTICS ; CEFPIRAMIDE ; DH5-ALPHA ; CR(VI)
AbstractThe microcalorimetric method has been used to study the effects of cefpiramide and ceftizoxime sodium on the E. coli growth. The results revealed that these two cephalosporins may alter the metabolic way of the E. coli. Moreover, the lethal doses of cefpiramide and ceftizoxime sodium are 2.000 and 0.2000 mu g mL(-1), respectively. Combining with the relationships between growth rate constant (k), the maximum power output (P (m) ), the time corresponding to the maximum power output (t (m) ) and cephalosporins concentration (C), one can draw the conclusion that the ceftizoxime sodium has a stronger inhibition effects on the growth of E. coli than that of cefpiramide and they both have the possibility to induce the drug fever.
Language英语
WOS IDWOS:000276771600028
Citation statistics
Cited Times:26[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/141981
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Mat & Thermochem Lab, Dalian 116023, Peoples R China
2.Zunyi Normal Coll, Dept Chem, Zunyi 563002, Peoples R China
3.Liaoning Normal Univ, Coll Chem & Chem Engn, Dalian 116029, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
5.Dalian Inst Drug Detect, Dalian 116021, Peoples R China
6.Sony Corp, Inst Higher Educ, Kanagawa 2438501, Japan
Recommended Citation
GB/T 7714
Yang, L. N.,Sun, Li Xian,Xu, Fen,et al. Inhibitory study of two cephalosporins on E. coli by microcalorimetry[J]. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,2010,100(2):589-592.
APA Yang, L. N..,Sun, Li Xian.,Xu, Fen.,Zhang, J..,Zhao, J. N..,...&Ozao, Riko.(2010).Inhibitory study of two cephalosporins on E. coli by microcalorimetry.JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,100(2),589-592.
MLA Yang, L. N.,et al."Inhibitory study of two cephalosporins on E. coli by microcalorimetry".JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY 100.2(2010):589-592.
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