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Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis
Yu, Fengjiao1; Kong, Liang1,2; Zou, Hanfa2; Lei, Xiaoyuan2
关键词Traditional Chinese Medicines (Tcms) Biological Fingerprinting Analysis Screening Bioactive Components/compounds Omics
刊名COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
2010-12-01
13期:10页:855-868
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Chemistry, Applied ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]IMMOBILIZED LIPOSOME CHROMATOGRAPHY ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; HUMAN SERUM-ALBUMIN ; IONIZATION MASS-SPECTROMETER ; LONGDAN-XIEGAN-DECOCTION ; DRUG DISCOVERY ; AFFINITY-CHROMATOGRAPHY ; STATIONARY-PHASE ; ACTIVE COMPOUNDS ; MOLECULAR BIOCHROMATOGRAPHY
英文摘要Traditional Chinese medicines (TCMs), a key branch of natural medicines, play an important role in the treatment of diseases because of their reliable clinical performance. Identification of their active compounds constitutes a bottleneck in the development of TCMs. Screening and analysis of active compounds is a challenge in TCM research. This review summarizes recent progress in the development of biological fingerprinting strategies for screening and analyzing bioactive compounds in TCMs using molecular recognition, metabolism and omics tools. The evaluated strategies include the following techniques: microdialysis/centrifugal ultrafiltration-HPLC, biochromatography, metabolic fingerprinting analysis, 2-dimensional biochromatography and omics fingerprinting analysis.
语种英语
WOS记录号WOS:000284622300005
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被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/142168
专题中国科学院大连化学物理研究所
作者单位1.Dalian Ocean Univ, Key Lab Offshore Marine Environm Res Liaoning Hig, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
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GB/T 7714
Yu, Fengjiao,Kong, Liang,Zou, Hanfa,et al. Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis[J]. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,2010,13(10):855-868.
APA Yu, Fengjiao,Kong, Liang,Zou, Hanfa,&Lei, Xiaoyuan.(2010).Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis.COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,13(10),855-868.
MLA Yu, Fengjiao,et al."Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis".COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 13.10(2010):855-868.
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