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题名: Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine
作者: van der Greef, Jan1, 2, 3, 5;  van Wietmarschen, Herman2, 3;  Schroen, Jan2;  Wang, Mei2, 5;  Hankemeier, Thomas2, 3;  Xu, Guowang2, 4
关键词: personalized medicine ;  Chinese medicine ;  diagnosis ;  systems biology ;  rheumatoid arthritis ;  metabolomics ;  phenotyping ;  targeted care
刊名: PLANTA MEDICA
发表日期: 2010-12-01
DOI: 10.1055/s-0030-1250450
卷: 76, 期:17, 页:2036-2047
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Plant Sciences ;  Chemistry, Medicinal ;  Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ;  Pharmacology & Pharmacy
英文摘要: Innovative systems approaches to develop medicine and health care are emerging from the integration of Chinese and Western medicine strategies, philosophies and practices. The two medical systems are highly complementary as the reductionist aspects of Western medicine are favourable in acute disease situations and the holistic aspects of Chinese medicine offer more opportunities in chronic conditions and for prevention. In this article we argue that diagnosis plays a key role in building the bridge between Chinese and Western medicine. Recent advances in the study of health, healing, placebo effects and patient-physician interactions will be discussed pointing out the development of a system-based diagnosis. Especially, a system biology-based diagnosis can be used to capture phenotype information, leading towards a scientific basis for a more refined patient characterization, new diagnostic tools and personalized heath strategies. Subtyping of rheumatoid arthritis patients based on Chinese diagnostic principles is discussed as an example. New insights from this process of integrating Western and Chinese medicine will pave the way for a patient-centred health care ecosystem.
关键词[WOS]: WILFORDII HOOK-F ;  RHEUMATOID-ARTHRITIS ;  DOUBLE-BLIND ;  PLACEBO ;  DISEASE ;  METABOLOMICS ;  PHARMACOLOGY ;  MINDFULNESS ;  DISCOVERY ;  CYTOKINES
语种: 英语
WOS记录号: WOS:000284941000012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/142234
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.TNO Qual Life, NL-3700 AJ Zeist, Netherlands
2.Sino Dutch Ctr Prevent & Personalized Med, Zeist, Netherlands
3.Leiden Univ, Netherlands Metabol Ctr, Div Analyt Biosci, Leiden, Netherlands
4.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China
5.SU BioMed, Zeist, Netherlands

Recommended Citation:
van der Greef, Jan,van Wietmarschen, Herman,Schroen, Jan,et al. Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine[J]. PLANTA MEDICA,2010,76(17):2036-2047.
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