DICP OpenIR
Oligonucleotide-functionalized gold nanoparticles-enhanced QCM-D sensor for mercury(II) ions with high sensitivity and tunable dynamic range
Chen, Qiang; Wu, Xiaojie; Wang, Dingzhong; Tang, Wei; Li, Na; Liu, Feng
刊名ANALYST
2011
DOI10.1039/c1an00010a
136期:12页:2572-2577
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]QUARTZ-CRYSTAL MICROBALANCE ; PIEZOELECTRIC SENSOR ; CIRCULAR-DICHROISM ; BASE-PAIRS ; METAL-IONS ; TRACE HG2+ ; TURN-ON ; BIOSENSOR ; REMEDIATION ; BINDING
英文摘要A quartz crystal microbalance with dissipation monitoring (QCM-D) sensor was developed for highly sensitive and specific detection of mercury(II) ions (Hg2+) with a tunable dynamic range, using oligonucleotide-functionalized gold nanoparticles (GNPs) for both frequency and dissipation amplification. The fabrication of the sensor employed a 'sandwich-type' strategy, and formation of T-Hg2+-T structures in linker DNA reduced the hybridization of the GNPs-tagged DNA on the gold electrode, which could be used as the molecular switch for Hg2+ sensing. This QCM-D mercury sensor showed a linear response of 10-200 nM, with detection limits of 4 nM and 7 nM for frequency and dissipation measurements, respectively. Moreover, the dynamic range of the sensor could be tuned by simply altering the concentration of linker DNA without designing new sensors in the cases where detection of Hg2+ at different levels is required. This sensor afforded excellent selectivity toward Hg2+ compared with other potential coexisting metal ions. The feasibility of the sensor was demonstrated by analyzing Hg2+-spiked tap- and lake-water samples with satisfactory recoveries. The proposed approach extended the application of the QCM-D system in metal ions sensing, and could be adopted for the detection of other analytes when complemented with the use of functional DNA structures.
语种英语
WOS记录号WOS:000291164900019
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/142553
专题中国科学院大连化学物理研究所
作者单位Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Coll Chem & Mol Engn,Minist Educ, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Chen, Qiang,Wu, Xiaojie,Wang, Dingzhong,et al. Oligonucleotide-functionalized gold nanoparticles-enhanced QCM-D sensor for mercury(II) ions with high sensitivity and tunable dynamic range[J]. ANALYST,2011,136(12):2572-2577.
APA Chen, Qiang,Wu, Xiaojie,Wang, Dingzhong,Tang, Wei,Li, Na,&Liu, Feng.(2011).Oligonucleotide-functionalized gold nanoparticles-enhanced QCM-D sensor for mercury(II) ions with high sensitivity and tunable dynamic range.ANALYST,136(12),2572-2577.
MLA Chen, Qiang,et al."Oligonucleotide-functionalized gold nanoparticles-enhanced QCM-D sensor for mercury(II) ions with high sensitivity and tunable dynamic range".ANALYST 136.12(2011):2572-2577.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, Qiang]的文章
[Wu, Xiaojie]的文章
[Wang, Dingzhong]的文章
百度学术
百度学术中相似的文章
[Chen, Qiang]的文章
[Wu, Xiaojie]的文章
[Wang, Dingzhong]的文章
必应学术
必应学术中相似的文章
[Chen, Qiang]的文章
[Wu, Xiaojie]的文章
[Wang, Dingzhong]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。