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题名: Extraction, purification and identification of bacterial signal molecules based on N-acyl homoserine lactones
作者: Wang, Jianhua2, 3;  Quan, Chunshan1;  Wang, Xue2, 3;  Zhao, Pengchao2, 3;  Fan, Shengdi1
刊名: MICROBIAL BIOTECHNOLOGY
发表日期: 2011-07-01
DOI: 10.1111/j.1751-7915.2010.00197.x
卷: 4, 期:4, 页:479-490
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Biotechnology & Applied Microbiology ;  Microbiology
研究领域[WOS]: Biotechnology & Applied Microbiology ;  Microbiology
英文摘要: Bacteria possess an extraordinary repertoire for intercellular communication and social behaviour. This repertoire for bacterial communication, termed as quorum sensing (QS), depends on specific diffusible signal molecules. There are many different kinds of signal molecules in the bacterial community. Among those signal molecules, N-acyl homoserine lactones (HSLs, in other publications also referred to as AHLs, acy-HSLs etc.) are often employed as QS signal molecules for many Gram-negative bacteria. Due to the specific structure and tiny amount of those HSL signal molecules, the characterization of HSLs has been the subject of extensive investigations in the last decades and has become a paradigm for bacteria intercellular signalling. In this article, different methods, including extraction, purification and characterization of HSLs, are reviewed. The review provides an insight into identification and characterization of new HSLs and other signal molecules for bacterial intercellular communication.
关键词[WOS]: SOLID-PHASE EXTRACTION ;  QUORUM-SENSING SIGNALS ;  GAS CHROMATOGRAPHY/MASS SPECTROMETRY ;  RESOLUTION MASS-SPECTROMETRY ;  GRAM-NEGATIVE BACTERIA ;  ACYLHOMOSERINE LACTONES ;  PSEUDOMONAS-AERUGINOSA ;  LIQUID-CHROMATOGRAPHY ;  BURKHOLDERIA-CEPACIA ;  DEPENDENT REGULATION
语种: 英语
WOS记录号: WOS:000292467200006
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/142717
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Nationalities Univ, Life Sci Coll, Dalian 116600, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

Recommended Citation:
Wang, Jianhua,Quan, Chunshan,Wang, Xue,et al. Extraction, purification and identification of bacterial signal molecules based on N-acyl homoserine lactones[J]. MICROBIAL BIOTECHNOLOGY,2011,4(4):479-490.
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