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题名: Biocompatibility of the micro-patterned NiTi surface produced by femtosecond laser
作者: Liang, Chunyong1;  Wang, Hongshui1;  Yang, Jianjun2;  Li, Baoe1;  Yang, Yang2, 3;  Li, Haipeng1
关键词: Micro-pattern ;  NiTi ;  Femtosecond laser ;  Biocompatibility
刊名: APPLIED SURFACE SCIENCE
发表日期: 2012-11-15
DOI: 10.1016/j.apsusc.2012.08.011
卷: 261, 页:337-342
收录类别: SCI
文章类型: Article
类目[WOS]: Chemistry, Physical ;  Materials Science, Coatings & Films ;  Physics, Applied ;  Physics, Condensed Matter
研究领域[WOS]: Chemistry ;  Materials Science ;  Physics
英文摘要: Biocompatibility of the micro-patterned NiTi surface produced by femtosecond laser (FSL) was studied in this work. The surface characteristics of the laser treated NiTi alloys were investigated by scanning electron microscopy (SEM), atom force microscopy (AFM), X-ray diffractometry (XRD) and X-ray photoelectron spectrum (XPS). The biocompatibility was evaluated by in vitro cell culture test. The results showed that, grooves, ripples, which covered by nanoparticles were formed on the sample surfaces, and the Ni/Ti ratio on the alloy surface increased with increasing laser energy. The crystal structure was not changed by laser treatment. However, the cell culture test proved that the micro-patterns induced by FSL were beneficial to improve the biocompatibility of NiTi alloys: the growth of osteoblasts oriented along the grooves, a large amount of synapses and filopodias were formed due to the ripples, holes and nanoparticles on the alloy surface, and the proliferation rate and alkaline phosphatase (ALP) content of cells were increased after FSL treatment. However, due to the toxicity of Ni ions on cell growth, the NiTi alloy surface should not be treated by laser fluence of more than 3.82 J/cm(2) to obtain the ideal biocompatibility. (C) 2012 Elsevier B. V. All rights reserved.
关键词[WOS]: IN-VITRO ;  OSTEOBLAST ADHESION ;  TITANIUM-ALLOY ;  PULSES ;  MICROSTRUCTURES ;  NANOPARTICLES ;  CYTOTOXICITY ;  RELEASE ;  METALS ;  CELLS
语种: 英语
WOS记录号: WOS:000310442500050
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/142894
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Hebei Univ Technol, Sch Mat Sci & Engn, Tianjin 300130, Peoples R China
2.Nankai Univ, Inst Modern Opt, Tianjin 300071, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China

Recommended Citation:
Liang, Chunyong,Wang, Hongshui,Yang, Jianjun,et al. Biocompatibility of the micro-patterned NiTi surface produced by femtosecond laser[J]. APPLIED SURFACE SCIENCE,2012,261:337-342.
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