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Insights into the regulation of human CNV-miRNAs from the view of their target genes
Wu, Xudong; Zhang, Dinglin; Li, Guohui
关键词Copy Number Variation Mirna Expression Variation Hapmap Ethnic Population
刊名BMC GENOMICS
2012-12-18
DOI10.1186/1471-2164-13-707
13
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology ; Genetics & Heredity
研究领域[WOS]Biotechnology & Applied Microbiology ; Genetics & Heredity
关键词[WOS]COPY-NUMBER VARIATION ; HUMAN GENOME ; MICROARRAY ANALYSIS ; MICRORNA TARGETS ; EXPRESSION ; REVEALS ; DROSOPHILA ; SELECTION ; DOSAGE ; MOUSE
英文摘要Background: microRNAs (miRNAs) represent a class of small (typically 22 nucleotides in length) non-coding RNAs that can degrade their target mRNAs or block their translation. Recent research showed that copy number alterations of miRNAs and their target genes are highly prevalent in cancers; however, the evolutionary and biological functions of naturally existing copy number variable miRNAs (CNV-miRNAs) among individuals have not been studied extensively throughout the genome.
语种英语
WOS记录号WOS:000315327300001
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/143046
专题中国科学院大连化学物理研究所
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Lab Mol Modeling & Design, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
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Wu, Xudong,Zhang, Dinglin,Li, Guohui. Insights into the regulation of human CNV-miRNAs from the view of their target genes[J]. BMC GENOMICS,2012,13.
APA Wu, Xudong,Zhang, Dinglin,&Li, Guohui.(2012).Insights into the regulation of human CNV-miRNAs from the view of their target genes.BMC GENOMICS,13.
MLA Wu, Xudong,et al."Insights into the regulation of human CNV-miRNAs from the view of their target genes".BMC GENOMICS 13(2012).
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