中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
学科主题: 物理化学
题名: Identification of Two Novel Modifications at Tryptophan Residues
作者: Zheng, Shuzhen1;  Zhang, Kai1, 2, 3;  Tian, Shanshan2, 3;  He, Xiwen1;  Zhang, Yukui1, 4
通讯作者: 张锴
关键词: Proteomics ;  Mass spectrometry ;  Post-translational modifications ;  Tryptophan modifications
刊名: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
发表日期: 2015-10-01
DOI: 10.1007/s13361-015-1217-8
卷: 26, 期:10, 页:1787-1790
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences ;  Technology
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical ;  Chemistry, Physical ;  Spectroscopy
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry ;  Spectroscopy
英文摘要: Protein post-translational modifications (PTMs) play important roles in cellular physiology. Mass spectrometry (MS) has been developed into a powerful tool to identify all possible protein modifications. Herein, we describe our efforts to deduce the structures of two unknown modifications at tryptophan (Trp) residues (W + 92 Da and W + 108 Da). The two modifications were further confirmed by aligning the MS/MS fragmentation of synthetic peptide with in-vivo peptide identified. Finally, the mimic experiment elucidated how two Trp modifications occur. This study, therefore, expands current knowledge of Trp modifications.
关键词[WOS]: POSTTRANSLATIONAL MODIFICATIONS ;  MASS-SPECTROMETRY ;  PROTEINS ;  OXIDATION ;  PRODUCTS ;  DAMAGE ;  PTMAP ;  MS
语种: 英语
WOS记录号: WOS:000361073200017
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/143694
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
2015MOK7tuIIZt.PDF(600KB)期刊论文作者接受稿开放获取View 联系获取全文

作者单位: 1.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China
2.Tianjin Med Univ, Dept Biochem & Mol Biol, Tianjin 300070, Peoples R China
3.Tianjin Med Univ, Tianjin Key Lab Med Epigenet, Tianjin 300070, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China

Recommended Citation:
Zheng, Shuzhen,Zhang, Kai,Tian, Shanshan,et al. Identification of Two Novel Modifications at Tryptophan Residues[J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY,2015,26(10):1787-1790.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Zheng, Shuzhen]'s Articles
 [Zhang, Kai]'s Articles
 [Tian, Shanshan]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Zheng, Shuzhen]‘s Articles
 [Zhang, Kai]‘s Articles
 [Tian, Shanshan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 2015MOK7tuIIZt.PDF
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace