DICP OpenIR
Subject Area物理化学
Turn-on Fluorescent Sensing of Glutathione S-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods
Qin, Long1,2; He, Xiwen1,2; Chen, Langxing1,2; Zhang, Yukui1,2,3; Chen LX(陈朗星)
KeywordFluorescence Resonance Energy Transfer Gold Nanoclusters Gold Nanorods Glutathione S-transferase Near-infrared
Source PublicationACS APPLIED MATERIALS & INTERFACES
2015-03-18
DOI10.1021/acsami.5b00269
Volume7Issue:10Pages:5965-5971
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Technology
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS Research AreaScience & Technology - Other Topics ; Materials Science
WOS KeywordRESONANCE ENERGY-TRANSFER ; SEMICONDUCTOR QUANTUM DOTS ; NANOPARTICLES ; SURFACE ; PROBES ; ELISA ; QUANTITATION ; BIOMOLECULES ; ASSEMBLIES ; EXPRESSION
AbstractA fluorescence resonance energy transfer (FRET) method based on gold nanoclusters capped glutathione (AuNCs@GSH) and amine-terminated gold nanorods (AuNRs) is designed for turn-on and near-infrared region (NIR) sensing of glutathione S-transferase (GST). The absorption band of AuNRs is tuned carefully to maximize the spectra overlap and enhance the efficiency of FRET. The FRET from multiple AuNCs to single AuNR quenches about 70% fluorescence emission of AuNCs. After GST is added, the strong specific interaction of GSH-GST can replace the AuNCs@GSH from AuNRs, FRET based on electrostatic interaction between AuNCs@GSH and AuNRs is switched off. Thus, emission enhancement of AuNCs@GSH is observed. The fluorescent enhancement is linearly with the increasing GST concentration over the range of 2-100 nM GST and the limit of detection for GST is about 1.5 nM.
Language英语
WOS IDWOS:000351420300041
Citation statistics
Cited Times:42[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/143703
Collection中国科学院大连化学物理研究所
Corresponding AuthorChen LX(陈朗星)
Affiliation1.Nankai Univ, State Key Lab Med Chem Biol, Tianjin Key Lab Biosensing & Mol Recognit, Res Ctr Analyt Sci,Coll Chem, Tianjin 300071, Peoples R China
2.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China
Recommended Citation
GB/T 7714
Qin, Long,He, Xiwen,Chen, Langxing,et al. Turn-on Fluorescent Sensing of Glutathione S-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods[J]. ACS APPLIED MATERIALS & INTERFACES,2015,7(10):5965-5971.
APA Qin, Long,He, Xiwen,Chen, Langxing,Zhang, Yukui,&陈朗星.(2015).Turn-on Fluorescent Sensing of Glutathione S-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods.ACS APPLIED MATERIALS & INTERFACES,7(10),5965-5971.
MLA Qin, Long,et al."Turn-on Fluorescent Sensing of Glutathione S-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods".ACS APPLIED MATERIALS & INTERFACES 7.10(2015):5965-5971.
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