中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
学科主题: 物理化学
题名: A novel polymeric monolith prepared with multi-acrylate crosslinker for retention-independent efficient separation of small molecules in capillary liquid chromatography
作者: Zhang, Haiyang1, 2;  Ou, Junjie2;  Wei, Yinmao1;  Wang, Hongwei2, 3;  Liu, Zhongshan2, 3;  陈连芳2, 3;  Zou, Hanfa2
通讯作者: 欧俊杰 ;  卫引茂 ;  邹汉法
关键词: Polymer monoliths ;  Capillary liquid chromatography ;  Dipentaerythritol penta-/hexa-acrylate ;  Photo-initiated polymerization
刊名: ANALYTICA CHIMICA ACTA
发表日期: 2015-07-09
DOI: 10.1016/j.aca.2015.04.001
卷: 883, 期:1, 页:90-98
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Low column efficiency for small molecules in reversed-phase chromatography is a major problem commonly encountered in polymer-based monoliths. Herein, a novel highly crosslinked porous polymeric monolith was in situ prepared by using a multi-acrylate monomer, dipentaerythritol penta-/hexa-acrylate (DPEPA), as crosslinker, which copolymerized with lauryl methacrylate (LMA) as functional monomer in a UV-transparent fused-silica capillary via photo-initiated free-radical polymerization within 5 min. The mechanical stability and permeability of the resulting poly(LMA-co-DPEPA) monolith were characterized in detail. One series of highly crosslinked poly(LMA-co-DPEPA) columns were prepared with relatively higher content of crosslinker (63.3%) in the precursor. Although they exhibited lower permeability, high column efficiency for alkylbenzenes was acquired in cLC, and the minimum plate height (column B) was in the range of 6.04-9.00 mm, corresponding to 111,000-165,000 N m(-1). Meanwhile, another series of poly(LMA-co-DPEPA) columns prepared with relatively lower content of crosslinker (52.7%) in the precursor exhibited higher permeability, but the minimum plate height (column E) was relatively low in the range of 10.75-20.04 mm for alkylbenzenes, corresponding to 50,000-93,000 N m(-1). Compared with common poly(LMA-co-EDMA) columns previously reported, the highly crosslinked poly(LMA-co-DPEPA) columns using a multi-acrylate monomer as crosslinker possessed remarkably high column efficiency for small molecules in cLC. By plotting of plate height (H) of alkylbenzenes versus the linear velocity (u) of mobile phase, the results revealed a retention-independent efficient performance of small molecules in the isocratic elution, indicating that the use of multi-functional crosslinker possibly prevents the generation of gel-like micropores in the poly(LMA-co-DPEPA) monolith, reducing the mass transfer resistance (C-term). (C) 2015 Elsevier B.V. All rights reserved.
关键词[WOS]: RING-OPENING POLYMERIZATION ;  LESS COMMON APPLICATIONS ;  LARGE SURFACE-AREA ;  METHACRYLATE MONOLITHS ;  STATIONARY PHASES ;  POROUS PROPERTIES ;  HYBRID MONOLITH ;  COLUMNS ;  HPLC ;  PERFORMANCE
语种: 英语
WOS记录号: WOS:000356236700011
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/143773
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
2015jDbDtAi5fQ.PDF(2520KB)期刊论文作者接受稿开放获取View 联系获取全文

作者单位: 1.Northwest Univ, Coll Chem & Mat Sci, Key Lab Synthet & Nat Funct Mol Chem, Minist Educ, Xian 710069, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China

Recommended Citation:
Zhang, Haiyang,Ou, Junjie,Wei, Yinmao,et al. A novel polymeric monolith prepared with multi-acrylate crosslinker for retention-independent efficient separation of small molecules in capillary liquid chromatography[J]. ANALYTICA CHIMICA ACTA,2015,883(1):90-98.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Zhang, Haiyang]'s Articles
 [Ou, Junjie]'s Articles
 [Wei, Yinmao]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Zhang, Haiyang]‘s Articles
 [Ou, Junjie]‘s Articles
 [Wei, Yinmao]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 2015jDbDtAi5fQ.PDF
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace