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学科主题: 物理化学
题名: Overexpression of OLC1 Promotes Tumorigenesis of Human Esophageal Squamous Cell Carcinoma
作者: Li, Xiao1, 2, 3, 5, 6;  Suo, Jing6;  Shao, Shujuan6;  Xue, Liyan2, 3, 4;  Chen, Wei1, 2, 3;  Dong, Lijia1, 2, 3;  Shi, Ji1, 2, 3, 6;  Fu, Ming1, 2, 3;  Lu, Ning2, 3, 4;  Zhan, Qimin1, 2, 3;  Tong, Tong1, 2, 3
通讯作者: 詹启敏 ;  童彤
刊名: PLOS ONE
发表日期: 2014-03-07
DOI: 10.1371/journal.pone.0090958
卷: 9, 期:3, 页:90958
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
英文摘要: Purpose: OLC1 was recently identified to be a potential oncogene. However, the role of OLC1 in human esophageal cell carcinoma (ESCC) is unknown. The aim of this study was therefore to evaluate the expression of OLC1 in human ESCC from normal, premalignant, and malignant lesions, and to clarify the mechanisms by which OLC1 contributes to the progression of ESCC.
关键词[WOS]: ENDOTHELIAL-GROWTH-FACTOR ;  CYTOCHROME-C RELEASE ;  AURORA-A ;  SACCHAROMYCES-CEREVISIAE ;  PROGNOSTIC-SIGNIFICANCE ;  CLINICAL-SIGNIFICANCE ;  CIGARETTE-SMOKE ;  PROTEIN SPARTIN ;  BCL-2 FAMILY ;  CYCLE ARREST
语种: 英语
WOS记录号: WOS:000332485800070
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/143855
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Med Sci, Inst Canc, State Key Lab Mol Oncol, Beijing 100021, Peoples R China
2.Chinese Acad Med Sci, Canc Hosp, Beijing 100730, Peoples R China
3.Peking Union Med Coll, Beijing 100021, Peoples R China
4.Chinese Acad Med Sci, Inst Canc, Dept Pathol, Beijing 100021, Peoples R China
5.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Liaoning, Peoples R China
6.Dalian Med Univ, Dept Histol & Embryol, Dalian, Liaoning, Peoples R China

Recommended Citation:
Li, Xiao,Suo, Jing,Shao, Shujuan,et al. Overexpression of OLC1 Promotes Tumorigenesis of Human Esophageal Squamous Cell Carcinoma[J]. PLOS ONE,2014,9(3):90958.
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