DICP OpenIR
Subject Area物理化学
Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry
Qiao, Xiaoqiang1,2; Wang, Rui1,2,3; Yan, Hongyuan1,2; Wang, Tao1,2; Zhao, Qun3; Zhang, Lihua3; Zhang, Yukui3; Qiao XQ(乔晓强); Zhang LH(张丽华)
Source PublicationRAPID COMMUNICATIONS IN MASS SPECTROMETRY
2014-02-15
DOI10.1002/rcm.6785
Volume28Issue:3Pages:256-264
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Spectroscopy
WOS KeywordELECTRON-TRANSFER DISSOCIATION ; CARBOXY GROUP DERIVATIZATION ; N-TERMINAL DERIVATIZATION ; MALDI-TOF MS ; CHEMICAL DERIVATIZATION ; SIGNAL ENHANCEMENT ; BOTTOM-UP ; LIQUID ; PHOSPHOPEPTIDES ; IONIZATION
AbstractRATIONALEChemical derivatization is a very promising technique for improving analysis of peptides by mass spectrometry (MS). In this study, a novel kind of imidazolium-based aromatic quaternary ammonium tag, 1-[3-[(2-iodo-1-oxoethyl)amino]propyl]-3-butylimidazolium bromide (IPBI), designed with strong gas-phase basicity and a permanent positive charge, was firstly synthesized and further used for derivatization of cysteinyl-peptides with improved ionization efficiency and higher charge states.
Language英语
WOS IDWOS:000328823200003
Citation statistics
Cited Times:9[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/144440
Collection中国科学院大连化学物理研究所
Corresponding AuthorQiao XQ(乔晓强); Zhang LH(张丽华)
Affiliation1.Hebei Univ, Key Lab Pharmaceut Qual Control Hebei Prov, Baoding 071002, Peoples R China
2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Qiao, Xiaoqiang,Wang, Rui,Yan, Hongyuan,et al. Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2014,28(3):256-264.
APA Qiao, Xiaoqiang.,Wang, Rui.,Yan, Hongyuan.,Wang, Tao.,Zhao, Qun.,...&张丽华.(2014).Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,28(3),256-264.
MLA Qiao, Xiaoqiang,et al."Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 28.3(2014):256-264.
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