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学科主题: 物理化学
题名: Mass spectrometry-based tag and its application to high efficient peptide analysis - A review
作者: Qiao, Xiaoqiang1, 2;  Qin, Xinying3;  She, Dandan1, 2;  Wang, Rui1, 2, 4;  Zhang, Xiaodan4;  Zhang, Lihua4;  Zhang, Yukui4
通讯作者: 乔晓强 ;  张丽华
关键词: Tag ;  High efficient analysis ;  Peptide ;  Mass spectrometry
刊名: TALANTA
发表日期: 2014-08-01
DOI: 10.1016/j.talanta.2014.03.012
卷: 126, 期:1, 页:91-102
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Chemical derivatization is a very promising technique for improving analysis of peptides by mass spectrometry (MS). Thereinto, development of novel tags compatible with MS and/or MS/MS has always been the focus point of study. In this review, the recent reported tags for derivatization of thiol groups of cysteine, carboxyl groups, and amino groups on peptides as well as peptides with post-translational modifications (PTMs) are summarized. Moreover, the tags used for derivatization of glycans or oligosaccharides released from glycoproteins are also reviewed. (C) 2014 Elsevier B.V. All rights reserved.
关键词[WOS]: ASSISTED-LASER-DESORPTION/IONIZATION ;  MALDI-TOF-MS ;  ELECTRON-TRANSFER DISSOCIATION ;  CARBOXY GROUP DERIVATIZATION ;  QUATERNARY AMMONIUM TAG ;  N-LINKED GLYCANS ;  PHOSPHORYLATED PEPTIDES ;  CHEMICAL DERIVATIZATION ;  STRUCTURAL DETERMINATION ;  PYRENE DERIVATIZATION
语种: 英语
WOS记录号: WOS:000337866200012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/144443
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Baoding 071002, Peoples R China
2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China
3.Hebei Univ, Coll Chem & Environm Sci, Baoding 071002, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 716023, Peoples R China

Recommended Citation:
Qiao, Xiaoqiang,Qin, Xinying,She, Dandan,et al. Mass spectrometry-based tag and its application to high efficient peptide analysis - A review[J]. TALANTA,2014,126(1):91-102.
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