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学科主题: 物理化学
题名: Metabolomics and traditional Chinese medicine
作者: Hu, Chunxiu1;  Xu, Guowang1
通讯作者: 许国旺
关键词: Analytical characterization ;  Bioactive component ;  Biochemistry ;  Chinese herbal medicine ;  Chromatographic fingerprinting ;  Holistic bioactivity ;  Metabolomics ;  Multi-component mixture ;  TCM syndrome ;  Traditional Chinese medicine
刊名: TRAC-TRENDS IN ANALYTICAL CHEMISTRY
发表日期: 2014-10-01
DOI: 10.1016/j.trac.2014.06.007
卷: 61, 期:1, 页:207-214
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Traditional Chinese medicine (TCM) has attracted increasing interest throughout the world because of its potential as complementary therapy of choice and a source for discovery of new drugs. However, the analytical characterization of TCM is still in its infancy due to its chemical nature of multi-component mixtures that often possess their own inherent holistic bioactivities. Metabolomics incorporates state-of-the-art approaches enabling systemic molecular characterization in complex samples and provides the option for an integrated view of the biochemistry in TCM. In this review, we present current metabolomics technologies in research on TCM related to chemical composition, bioactive components and efficacy. We also highlight the potential role of metabolomics technologies in evidence-based studies of TCM syndromes. (C) 2014 Elsevier B.V. All rights reserved.
关键词[WOS]: PERFORMANCE LIQUID-CHROMATOGRAPHY ;  POTENTIAL BIOACTIVE COMPONENTS ;  IONIZATION-MASS-SPECTROMETRY ;  SYSTEMS BIOLOGY ;  CELL EXTRACTION ;  ARRAY DETECTION ;  URINARY METABONOMICS ;  HERBAL MEDICINE ;  RATS ;  METABOLITES
语种: 英语
WOS记录号: WOS:000343350200028
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/144477
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China

Recommended Citation:
Hu, Chunxiu,Xu, Guowang. Metabolomics and traditional Chinese medicine[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2014,61(1):207-214.
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