DICP OpenIR
Subject Area物理化学
一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用
许国旺; 李华; 石先哲; 单圆鸿
Application NumberCN201110410396.3
Patent NumberCN201110410396.3
Application Date2011-12-09
2014-12-10
Rights Holder中国科学院大连化学物理研究所
Subtype发明
PCT Attributes
Copyright Date2014-12-10
一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用; 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用
Date Available2014-12-10
Other AbstractThe invention belongs to the technical field of inorganic material and analysis, and specifically relates to sea-urchin-shaped core-shell type magnetic microspheres, preparation method and application thereof in the respect of phosphorylated polypeptide selective enrichment. According to the magnetic microspheres, a layer of a SiO2 material is coated on the surface of Fe3O4 magnetic microspheres with a sol-gel method; a layer of anatase nuclei is deposited; and through hydrothermal growth, rutile nano-rods are grown on the surface of the nano-grade nuclei, such that the magnetic microsphere particles with the sea urchin shapes are formed. The magnetic material has large specific surface area, and rapid external magnetic field response. During selective enrichment of trace amount of phosphorylated polypeptide in a biological sample, the treatment is simple, and specificity is high. The material has good practical value and application prospect in the fields such as proteomics. | 本发明属于无机材料和分析技术领域,具体涉及一种海胆状核-壳型的磁性微球及其制备方法和在磷酸化多肽选择性富集方面的应用。该磁性微球是在Fe3O4磁性微球表面以溶胶凝胶法包覆一层SiO2材料,然后再沉积一层锐钛矿晶核,最后通过水热生长使得纳米晶种在表面长成金红石纳米棒,形成具有海胆状外形的磁性微球颗粒。该种磁性材料比表面积大,具有快速的外部磁场响应,对生物样品中痕量磷酸化多肽选择性富集时处理简单、特异性强。该材料在蛋白组学等领域有良好的实用价值和应用前景。
Document Type专利
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/145264
Collection中国科学院大连化学物理研究所
Affiliation中国科学院大连化学物理研究所
Recommended Citation
GB/T 7714
许国旺,李华,石先哲,等. 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用, 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用, 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用, 一种海胆状核-壳型Fe3O4@TiO2磁性微球及其制备和应用. CN201110410396.3[P]. 2014-12-10.
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