DICP OpenIR
Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics
Cheng, Chang-Li; Zhang, Ming-Zhen; Zhao, Guang-Jiu
刊名RSC ADVANCES
2014
DOI10.1039/c3ra42679c
4期:13页:6513-6516
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]ANISOTROPIC DEFORMATION ; INFRARED-SPECTROSCOPY ; COMPLEX-FORMATION ; GFP ; PATHWAYS ; SIMULATION ; LANDSCAPE ; LIGHT
英文摘要Green fluorescent protein (GFP) is used as a biosensor for protein-protein interactions, co-translational folding and localization of different structures in cells, in which the mechanical stability and thermal conductivity of the beta-barrels play a vital role. In this work, we first explore themechanical and thermal properties of beta-barrels in GFP by using the molecular dynamics simulations. Our results show that the beta-barrel is destabilized once one strand is detached. Moreover, we also observe that the temperature relaxation processes of an unfolded state and the native state are nearly the same. Our dynamics simulations improve the understanding of mechanical stability of beta-barrels and help to find nanoscale mechanism controlling energy transport in biomolecules.
语种英语
WOS记录号WOS:000329931000023
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/145463
专题中国科学院大连化学物理研究所
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Cheng, Chang-Li,Zhang, Ming-Zhen,Zhao, Guang-Jiu. Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics[J]. RSC ADVANCES,2014,4(13):6513-6516.
APA Cheng, Chang-Li,Zhang, Ming-Zhen,&Zhao, Guang-Jiu.(2014).Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics.RSC ADVANCES,4(13),6513-6516.
MLA Cheng, Chang-Li,et al."Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics".RSC ADVANCES 4.13(2014):6513-6516.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Cheng, Chang-Li]的文章
[Zhang, Ming-Zhen]的文章
[Zhao, Guang-Jiu]的文章
百度学术
百度学术中相似的文章
[Cheng, Chang-Li]的文章
[Zhang, Ming-Zhen]的文章
[Zhao, Guang-Jiu]的文章
必应学术
必应学术中相似的文章
[Cheng, Chang-Li]的文章
[Zhang, Ming-Zhen]的文章
[Zhao, Guang-Jiu]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。