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题名: Inhibitory effect of Ecliptae herba extract and its component wedelolactone on pre-osteoclastic proliferation and differentiation
作者: Liu, Yan-Qiu1, 2;  Zhan, Li-Bin1, 3;  Liu, Tiegang4;  Cheng, Meng-Chun2;  Liu, Xiao-Yan2;  Xiao, Hong-Bin2
关键词: Ecliptae herba ;  Wedelolactone ;  Osteoclasts ;  Differentiation
刊名: JOURNAL OF ETHNOPHARMACOLOGY
发表日期: 2014-11-18
DOI: 10.1016/j.jep.2014.09.033
卷: 157, 页:206-211
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Plant Sciences ;  Chemistry, Medicinal ;  Integrative & Complementary Medicine ;  Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ;  Pharmacology & Pharmacy ;  Integrative & Complementary Medicine
英文摘要: Ethnopharmacological relevance: Ecliptae herba, also known as "Mo-Han-Lian", has long been used in China to nourish Kidney and thereafter strengthen bones. Accumulating evidence indicates that extracts of Ecliptae herba have antiosteoporotic effect. However, the effective compounds and cellular mode of action are still unclear. To investigate the effect of ethyl acetate extract of Ecliptae herba (EAE) and its component wedelolactone on proliferation and differentiation of preosteoclastic RAW264.7 cells as well as proliferation of bone marrow stromal cells (BMSC).
关键词[WOS]: MESENCHYMAL STEM-CELLS ;  ALENDRONATE THERAPY ;  OSTEOPOROSIS ;  PROSTRATA ;  RATS
语种: 英语
WOS记录号: WOS:000347022700024
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/145506
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Med Univ, Coll Inst Integrat Med, Dalian 116044, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian, Liaoning, Peoples R China
3.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Liaoning Provin, Peoples R China
4.Beijing Univ Chinese Med, Beijing 100029, Peoples R China

Recommended Citation:
Liu, Yan-Qiu,Zhan, Li-Bin,Liu, Tiegang,et al. Inhibitory effect of Ecliptae herba extract and its component wedelolactone on pre-osteoclastic proliferation and differentiation[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014,157:206-211.
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