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Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases
Li, Peng1,2; Chen, Jianxin3; Wang, Jinan1,2; Zhou, Wei2; Wang, Xia1,2; Li, Bohui1,2; Tao, Weiyang1,2; Wang, Wei3; Wang, Yonghua1,2; Yang, Ling4
KeywordCardiovascular Diseases Drug Discovery And Combination Systems Pharmacology Systems Biology
Source PublicationJOURNAL OF ETHNOPHARMACOLOGY
2014-01-10
DOI10.1016/j.jep.2013.07.001
Volume151Issue:1Pages:93-107
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
WOS KeywordNETWORK PERSPECTIVES ; SIGNALING PATHWAYS ; CORONARY-ARTERY ; MEDICINE ; METABOLISM ; ABSORPTION ; BIOLOGY ; MECHANISMS ; DANSHEN ; GENOME
AbstractEthnopharmacological relevance: Multi-target therapeutics is a promising paradigm for drug discovery which is expected to produce greater levels of efficacy with fewer adverse effects and toxicity than monotherapies. Medical herbs featuring multi-components and multi-targets may serve as valuable resources for network-based multi-target drug discovery.
Language英语
WOS IDWOS:000331017200008
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Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/145563
Collection中国科学院大连化学物理研究所
Affiliation1.Northwest A&F Univ, Ctr Bioinformat, Yangling 712100, Shaanxi, Peoples R China
2.Northwest A&F Univ, Coll Life Sci, Yangling 712100, Shaanxi, Peoples R China
3.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Li, Peng,Chen, Jianxin,Wang, Jinan,et al. Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014,151(1):93-107.
APA Li, Peng.,Chen, Jianxin.,Wang, Jinan.,Zhou, Wei.,Wang, Xia.,...&Yang, Ling.(2014).Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases.JOURNAL OF ETHNOPHARMACOLOGY,151(1),93-107.
MLA Li, Peng,et al."Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases".JOURNAL OF ETHNOPHARMACOLOGY 151.1(2014):93-107.
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