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Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases
Li, Peng1,2; Chen, Jianxin3; Wang, Jinan1,2; Zhou, Wei2; Wang, Xia1,2; Li, Bohui1,2; Tao, Weiyang1,2; Wang, Wei3; Wang, Yonghua1,2; Yang, Ling4
关键词Cardiovascular Diseases Drug Discovery And Combination Systems Pharmacology Systems Biology
刊名JOURNAL OF ETHNOPHARMACOLOGY
2014-01-10
DOI10.1016/j.jep.2013.07.001
151期:1页:93-107
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
关键词[WOS]NETWORK PERSPECTIVES ; SIGNALING PATHWAYS ; CORONARY-ARTERY ; MEDICINE ; METABOLISM ; ABSORPTION ; BIOLOGY ; MECHANISMS ; DANSHEN ; GENOME
英文摘要Ethnopharmacological relevance: Multi-target therapeutics is a promising paradigm for drug discovery which is expected to produce greater levels of efficacy with fewer adverse effects and toxicity than monotherapies. Medical herbs featuring multi-components and multi-targets may serve as valuable resources for network-based multi-target drug discovery.
语种英语
WOS记录号WOS:000331017200008
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文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/145563
专题中国科学院大连化学物理研究所
作者单位1.Northwest A&F Univ, Ctr Bioinformat, Yangling 712100, Shaanxi, Peoples R China
2.Northwest A&F Univ, Coll Life Sci, Yangling 712100, Shaanxi, Peoples R China
3.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Liaoning, Peoples R China
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Li, Peng,Chen, Jianxin,Wang, Jinan,et al. Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014,151(1):93-107.
APA Li, Peng.,Chen, Jianxin.,Wang, Jinan.,Zhou, Wei.,Wang, Xia.,...&Yang, Ling.(2014).Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases.JOURNAL OF ETHNOPHARMACOLOGY,151(1),93-107.
MLA Li, Peng,et al."Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases".JOURNAL OF ETHNOPHARMACOLOGY 151.1(2014):93-107.
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