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题名: Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases
作者: Li, Peng1, 2;  Chen, Jianxin3;  Wang, Jinan1, 2;  Zhou, Wei2;  Wang, Xia1, 2;  Li, Bohui1, 2;  Tao, Weiyang1, 2;  Wang, Wei3;  Wang, Yonghua1, 2;  Yang, Ling4
关键词: Cardiovascular diseases ;  Drug discovery and combination ;  Systems pharmacology ;  Systems biology
刊名: JOURNAL OF ETHNOPHARMACOLOGY
发表日期: 2014-01-10
DOI: 10.1016/j.jep.2013.07.001
卷: 151, 期:1, 页:93-107
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Plant Sciences ;  Chemistry, Medicinal ;  Integrative & Complementary Medicine ;  Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ;  Pharmacology & Pharmacy ;  Integrative & Complementary Medicine
英文摘要: Ethnopharmacological relevance: Multi-target therapeutics is a promising paradigm for drug discovery which is expected to produce greater levels of efficacy with fewer adverse effects and toxicity than monotherapies. Medical herbs featuring multi-components and multi-targets may serve as valuable resources for network-based multi-target drug discovery.
关键词[WOS]: NETWORK PERSPECTIVES ;  SIGNALING PATHWAYS ;  CORONARY-ARTERY ;  MEDICINE ;  METABOLISM ;  ABSORPTION ;  BIOLOGY ;  MECHANISMS ;  DANSHEN ;  GENOME
语种: 英语
WOS记录号: WOS:000331017200008
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/145563
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Northwest A&F Univ, Ctr Bioinformat, Yangling 712100, Shaanxi, Peoples R China
2.Northwest A&F Univ, Coll Life Sci, Yangling 712100, Shaanxi, Peoples R China
3.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Liaoning, Peoples R China

Recommended Citation:
Li, Peng,Chen, Jianxin,Wang, Jinan,et al. Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases[J]. JOURNAL OF ETHNOPHARMACOLOGY,2014,151(1):93-107.
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