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Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides
Xiong, Zhichao1,2; Ji, Yongsheng2,3; Fang, Chunli2; Zhang, Quanqing2; Zhang, Lingyi1; Ye, Mingliang2; Zhang, Weibing1,2; Zou, Hanfa2
KeywordCore-shell Structures Magnetic Properties Metal-organic Frameworks Nanoparticles Peptides
Source PublicationCHEMISTRY-A EUROPEAN JOURNAL
2014-06-10
DOI10.1002/chem.201400389
Volume20Issue:24Pages:7389-7395
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Multidisciplinary
WOS Research AreaChemistry
WOS KeywordMESOPOROUS SILICA MICROSPHERES ; TOF MS ANALYSIS ; MASS-SPECTROMETRY ; CHROMATOGRAPHIC-SEPARATION ; BIOMEDICAL APPLICATIONS ; NANOPARTICLES DESIGN ; SIO2 SHELL ; SERUM ; HYBRID ; EXTRACTION
AbstractFacile preparation of core-shell magnetic metal-organic framework nanospheres by a layer-by-layer approach is presented. The nanospheres have high surface area (285.89 cm(2)g(-1)), large pore volume (0.18 cm(3)g(-1)), two kinds of mesopores (2.50 and 4.72 nm), excellent magnetic responsivity (55.65 emu g(-1)), structural stability, and good dispersibility. The combination of porosity, hydrophobicity, and uniform magnetism was exploited for effective enrichment of peptides with simultaneous exclusion of high molecular weight proteins. The nanospheres were successfully applied in the selective enrichment of endogenous peptides in human serum.
Language英语
WOS IDWOS:000337617500026
Citation statistics
Cited Times:43[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/145583
Collection中国科学院大连化学物理研究所
Affiliation1.E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Dept Chem & Mol Engn, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
3.Henan Univ Tradit Chinese Med, Coll Pharm, Zhengzhou 450008, Peoples R China
Recommended Citation
GB/T 7714
Xiong, Zhichao,Ji, Yongsheng,Fang, Chunli,et al. Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides[J]. CHEMISTRY-A EUROPEAN JOURNAL,2014,20(24):7389-7395.
APA Xiong, Zhichao.,Ji, Yongsheng.,Fang, Chunli.,Zhang, Quanqing.,Zhang, Lingyi.,...&Zou, Hanfa.(2014).Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides.CHEMISTRY-A EUROPEAN JOURNAL,20(24),7389-7395.
MLA Xiong, Zhichao,et al."Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides".CHEMISTRY-A EUROPEAN JOURNAL 20.24(2014):7389-7395.
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