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题名: Fabrication of a novel magnetic yolk-shell Fe3O4@mTiO(2)@mSiO(2) nanocomposite for selective enrichment of endogenous phosphopeptides from a complex sample
作者: Wan, Hao1, 2;  Li, Jinan2;  Yu, Wenguang2;  Liu, Zheyi2;  Zhang, Quanqing2;  Zhang, Weibing1;  Zou, Hanfa2
刊名: RSC ADVANCES
发表日期: 2014
DOI: 10.1039/c4ra08692a
卷: 4, 期:86, 页:45804-45808
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: A yolk-shell nanocomposite composed of a magnetic mesoporous anatase TiO2 (Fe3O4@mTiO(2)) core, a medium cavity and an outermost mesoporous silica (mSiO(2)) shell was successfully fabricated. Due to a combination of the strong magnetic response, improved diffusion of peptides, numerous affinity sites towards phosphopeptides and the size-exclusion effect, the nanocomposite demonstrated high enrichment efficacy and selectivity towards endogenous phosphopeptides from human serum.
关键词[WOS]: AFFINITY-CHROMATOGRAPHY PLATFORM ;  TIO2 NANOCRYSTAL CLUSTERS ;  PHOSPHORYLATED PEPTIDES ;  COMPOSITE MICROSPHERES ;  FAST SEPARATION ;  CORE-SHELL ;  GRAPHENE ;  CAPTURE
语种: 英语
WOS记录号: WOS:000342761600025
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/145759
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China

Recommended Citation:
Wan, Hao,Li, Jinan,Yu, Wenguang,et al. Fabrication of a novel magnetic yolk-shell Fe3O4@mTiO(2)@mSiO(2) nanocomposite for selective enrichment of endogenous phosphopeptides from a complex sample[J]. RSC ADVANCES,2014,4(86):45804-45808.
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