DICP OpenIR
Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry
Qiao, Xiaoqiang1,2; Wang, Rui1,2,3; Li, Guangyue4; Yan, Hongyuan1,2; Zhou, Yuan3; Zhang, Lihua3; Zhang, Yukui3
刊名ANALYST
2014
DOI10.1039/c3an01907a
139期:4页:705-708
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]ELECTRON-TRANSFER DISSOCIATION ; CARBOXY GROUP DERIVATIZATION ; QUATERNARY AMMONIUM TAG ; AMINO-ACIDS ; PEPTIDES ; MATRIX ; IONIZATION ; REAGENTS ; PHOSPHOPEPTIDES ; QUANTITATION
英文摘要New types of imidazolium-based iodoacetamide tags were designed, synthesized and further exploited for cysteinyl-peptide analysis with superior labeling efficiency, high stability, improved ionization efficiency, and increased charge states bymass spectrometry. For the first time, the effects of these kinds of tags on the mass spectrometry performance of the derivatized peptides were investigated, which is of great importance to help us design more efficient tags for the analysis of peptides or proteins, especially for those with low abundance.
语种英语
WOS记录号WOS:000330042500002
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/145779
专题中国科学院大连化学物理研究所
作者单位1.Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China
2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
4.Hebei United Univ, Coll Chem Engn, Tangshan 063009, Peoples R China
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GB/T 7714
Qiao, Xiaoqiang,Wang, Rui,Li, Guangyue,et al. Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry[J]. ANALYST,2014,139(4):705-708.
APA Qiao, Xiaoqiang.,Wang, Rui.,Li, Guangyue.,Yan, Hongyuan.,Zhou, Yuan.,...&Zhang, Yukui.(2014).Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry.ANALYST,139(4),705-708.
MLA Qiao, Xiaoqiang,et al."Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry".ANALYST 139.4(2014):705-708.
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