DICP OpenIR
Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry
Qiao, Xiaoqiang1,2; Wang, Rui1,2,3; Li, Guangyue4; Yan, Hongyuan1,2; Zhou, Yuan3; Zhang, Lihua3; Zhang, Yukui3
Source PublicationANALYST
2014
DOI10.1039/c3an01907a
Volume139Issue:4Pages:705-708
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordELECTRON-TRANSFER DISSOCIATION ; CARBOXY GROUP DERIVATIZATION ; QUATERNARY AMMONIUM TAG ; AMINO-ACIDS ; PEPTIDES ; MATRIX ; IONIZATION ; REAGENTS ; PHOSPHOPEPTIDES ; QUANTITATION
AbstractNew types of imidazolium-based iodoacetamide tags were designed, synthesized and further exploited for cysteinyl-peptide analysis with superior labeling efficiency, high stability, improved ionization efficiency, and increased charge states bymass spectrometry. For the first time, the effects of these kinds of tags on the mass spectrometry performance of the derivatized peptides were investigated, which is of great importance to help us design more efficient tags for the analysis of peptides or proteins, especially for those with low abundance.
Language英语
WOS IDWOS:000330042500002
Citation statistics
Cited Times:11[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/145779
Collection中国科学院大连化学物理研究所
Affiliation1.Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China
2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
4.Hebei United Univ, Coll Chem Engn, Tangshan 063009, Peoples R China
Recommended Citation
GB/T 7714
Qiao, Xiaoqiang,Wang, Rui,Li, Guangyue,et al. Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry[J]. ANALYST,2014,139(4):705-708.
APA Qiao, Xiaoqiang.,Wang, Rui.,Li, Guangyue.,Yan, Hongyuan.,Zhou, Yuan.,...&Zhang, Yukui.(2014).Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry.ANALYST,139(4),705-708.
MLA Qiao, Xiaoqiang,et al."Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry".ANALYST 139.4(2014):705-708.
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